Synthesis  of  Some  New F used  P yridines  and  Prediction  their  Biological Activity via PASS INET
A new series of fused heterocyclic compounds containing pyridine moieties were prepared via the reaction of 2-amino-6-(methylthio)-4-phenylpyridine-3,5-dicarbonitrile with some halo reagents, active methylenes, acetic anhydride, phenylisothiocyanate, hydrazine hydrate or thioacetamide. Accompanied with Predictions of the activity spectra of some selected compounds using PASS Pa > 70%, showing high probability of Atherosclerosis treatment, Antineoplastic, DNA intercalator, Protein kinase inhibitor and ... إقراء المزيد