ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: amino acid


Metal based pharmacologically active agents: Synthesis, structural characterization, molecular modeling, CT-DNA binding studies and in vitro antimicrobial screening of iron(II) chelates
In recent years, great interest has been focused on Fe(II) Schiff base amino acid complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 5-bromosalicylaldehyde (bs) and α-amino acids (l-alanine (ala), l-phenylalanine (phala), l-aspartic acid (aspa), l-histidine (his) and l-arginine (arg)). The ... Read more

Design, characterization, teratogenicity testing, antibacterial, antifungal and DNA interaction of few high spin Fe(II) Schiff base amino acid complexes
In this study, new Fe(II) Schiff base amino acid chelates derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized via elemental, thermogravimetric analysis, molar conductance, IR, electronic, mass spectra and magnetic moment measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. Correlation of all spectroscopic data suggested ... Read more

2018-09-16 14:36:08 Keywords Fe(II) complexes, Toxicity, DNA interaction, amino acid, Schiff base,
Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes
New Fe(II) Schiff base amino acid complexes derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized by elemental analysis, IR, electronic spectra, and conductance measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. The investigated Schiff bases exhibited tridentate coordination mode with the general formulae [Fe(HL)2]·nH2O for ... Read more

DNA binding ability mode, spectroscopic studies, hydrophobicity, and in vitro antibacterial evaluation of some new Fe(II) complexes bearing ONO donors amino acid Schiff bases
New series of Fe(II) complexes and Schiff base amino acids have been designed and synthesized from the bioactive ligands by condensation of 5-bromo-2-hydroxybenzaldehyde and α-amino acids (l-alanine (ala), l-phenylalanine (phala), l-aspartic acid (aspa), l-histidine (his) and l-arginine (arg)). Elemental analyses, infrared, ultraviolet–visible spectra, as well as conductivity and magnetic susceptibility measurements are used to elucidate the structure of the newly ... Read more

2018-08-29 12:49:50 Keywords amino acid, Schiff base,
Synthesis and characterization of some novel amino acid Schiff base Fe(II) complexes
New Fe(II) complexes of N-salicylidene- and N-naphthylideneamino acids (H2L) were prepared and characterized by elemental, electronic and IR spectral analyses, conductance and magnetic moment measurements and spectrophotometric determination of the stoichiometry. The stability and solubility of the prepared complexes were determined. The investigated Schiff bases exhibited monodentate divalent tridentate coordination and formed chelates of octahedral structures of the general formulae ... Read more