Survivin, a member of the inhibitor of apoptosis protein family, has an important role in cell cycle regulation. Insulin-like growth factor-I (IGF-I) is a polypeptide hormone with wide range of biologic effects including stimulation of lipogenesis in sebaceous glands. Their overexpression in some fibrotic disorders suggests a possible implication of both IGF-I and survivin in the pathogenesis of acne and/or ... إقراء المزيد

Background: Acne vulgaris is the most common dermatological condition encoun- tered in adolescents. Aim: It was to determine the prevalence of acne vulgaris and its impact of the quality of life among adolescents attending secondary schools in Sohag Province, Upper Egypt. Patients and methods: This was a cross-sectional study conducted in randomly selected governmental and technical secondary schools in Sohag ... إقراء المزيد