ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: 3


Utilization of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidinone as a cap moiety in design of novel histone deacetylase inhibitors
A series of novel 5,6,7,8-Tetrahydro[1]benzothieno[2,3_-d_]pyrimidin-4(3_H_)-one derivatives bearing a hydroxamic acid, 2-aminoanilide and hydrazide moieties as zinc-binding group (ZBG) were designed, synthesized and evaluated for the HDAC inhibition activity and antiproliferative activity. Most of the tested compounds displayed strong to moderate HDAC inhibitory activity. Some of these compounds showed potent anti-proliferative activity against human HepG2, MCF-7 and HCT-116 cell lines. In ... Read more

Design, Synthesis and Antibacterial Evaluation of some new 3,5-Diphenylcyclohex-2-en-1-one Derivatives
Design, Synthesis and Antibacterial Evaluation of some new 3,5-Diphenylcyclohex-2-en-1-one Derivatives Read more

Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network
Multiple studies reporting mitochondrial impairment in Parkinson’s disease (PD) involve knockout or knockdown models to inhibit the expression of mitochondrial-related genes, including parkin, PINK1, and DJ-1 ones. Melatonin has significant neuroprotective properties, which have been related to its ability to boost mitochondrial bioenergetics. The meaning and molecular targets of melatonin in PD are yet unclear. Zebrafish are an outstanding model ... Read more

فاعلية برنامج مقترح في الدراسات الاجتماعية علي تنمية بعض مهارات التفكير السياسي والانتماء الوطني لدي طلاب كلية التربية
مستخلص البحث العنوان: فاعلية برنامج مقترح في الدراسات الاجتماعية علي تنمية بعض مهارات التفكير السياسي والانتماء الوطني لدي طلاب كلية التربية . إعداد: د/خالد عبد اللطيف محمد عمران– أستاذ مساعد المناهج وطرق تدريس الدراسات الاجتماعية – كلية التربية – جامعة سوهاج. د/ نجاة عبده عارف إسماعيل - دكتوراه الفلسفة في التربية تخصص مناهج وطرق تدريس وموجه دراسات اجتماعية - إدارة ... Read more