Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by joint inflammation and destruction resulting in degradation of extracellular cartilage matrix. Osteoarthritis (OA) is also associated with degradation of molecular components of cartilage matrix with eventual loss of joint cartilage function. Matrix metalloproteinases (MMPs) are a family of proteinases modulated enzymes that play an important role in the pathogenesis ... Read more

Abstract: Colon cancer cells resistance to apoptosis inducing factors, particularly those working through the extrinsic apoptotic rout, such as Tumour necrosis factor alpha (TNF-α), may due to that these cells lack of the presence of FAS receptor on their membrane, to which TNF-α binds and causes the recruitment of caspase-8 and other caspases cascade required in apoptotic cell death. In ... Read more

the main aim of study that we detected the role of vaspin and TNF alpha in detection of nephropathy in type 2 DM Read more