ghada_galal

Ghada Galal

Professor - Head of Tropical Medicine and Gastroenterology Department

Faculty of medicine

Address: Sohag, Egypt

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Publications Which contain the keyword: radiotherapy


Néphropathie post-radique Radiation-induced nephropathy
Background. The kidneys are doselimiting organs when total body irradiation or irradiation of the digestive tract is planned. The incidence of radiation-induced toxicity is probably underestimated due to its latency and confounding factors like chemotherapy. Material and methods. A search of the literature for radiation induced renal toxicity was performed. Results. Most toxicities occur around 18 months. Renal mobility is ... Read more

2018-10-31 07:56:22 Keywords Dental care, Compliance, Custom trays, radiotherapy,
Compliance with fluoride custom trays in irradiated head and neck cancer patients
Purpose The purpose of this study is to assess compliance with fluoride gel custom trays in irradiated head and neck cancer patients. Methods and materials One hundred fifty-five consecutive patients on remission following radiation therapy of head and neck cancers were assessed retrospectively for dental care practices prior to radiation and prospectively for long-term compliancewith customtrays fromNovember 2009 to January ... Read more

2018-10-31 09:31:53 Keywords cardiac toxicity, sarcoma, radiotherapy, dose, target volume,
Irradiation des sarcomes cardiaques de l’adulte Radiation therapy of cardiac sarcomas
tPurpose. – Primary cardiac sarcomas represent less than 10 yearly cases in France. Their median survivalis approximately 18 months. The treatment consists of surgery when possible. The role of chemotherapyand radiation therapy is controversial, especially with respect to limiting cardiac radiation dose that istheoretically incompatible with the requirement of a tumoricidal dose for sarcoma. A recent series of 124cases of ... Read more

2018-10-26 22:49:22 Keywords Head and Neck, radiotherapy, Chemotherapy, gemcitabine, Cisplatin,
Comparative study of Gemcitabine versus Cisplatin concurrent with radiotherapy for locally advanced head and neck cancer
Purpose: In our study we copmared low-dose gemcitabine-based chemoradiotherapy with cisplatin-based chemotherapy as regards response rate, survival and toxicity profile in locally advanced head and neck cancer Methodology: sixity patients with locally advanced head and neck cancer were included in this prospective comparative randomized study. In the period from January 2011 to September2013 Results: The patients were treated in two ... Read more

2018-10-14 18:38:28 Keywords melatonin, radiotherapy, small intestine toxicity,
Melatonin protects rats from radiotherapy-induced small intestine toxicity
Radiotherapy-induced gut toxicity is among the most prevalent dose-limiting toxicities following radiotherapy. Prevention of radiation enteropathy requires protection of the small intestine. However, despite the prevalence and burden of this pathology, there are currently no effective treatments for radiotherapy-induced gut toxicity, and this pathology remains unclear. The present study aimed to investigate the changes induced in the rat small intestine ... Read more

2018-10-14 17:57:03 Keywords Cancer cells, Chemotherapy, melatonin, radiotherapy,
Melatonin enhances the toxicity of radio-and chemotherapy in head and neck cancer cells
After reported a melatonin’s gel that protects normal cells from oral mucositis induced by radio- or chemotherapy, we wondered about how melatonin affects tumoral cells. It is well known that both radio- and chemotherapy act at different intracellular levels such as nucleus, membranes and mitochondria. On the other hand, mitochondrion is the main melatonin target. So we evaluated here whether ... Read more

2018-09-07 11:36:08 Keywords Cisplatin, gemcitabine, Chemotherapy, radiotherapy, Head and Neck,
Comparative study of Gemcitabine versus Cisplatin concurrent with radiotherapy for locally advanced head and neck cancer
ABSTRACT PURPOSE: In our study we compared low-dose gemcitabine-based chemoradiotherapy with cisplatin-based chemoradiotherapy as regards response rate, survival and toxicity profile in locally advanced head and neck cancer. METHODOLOGY: sixty patients with locally advanced head and neck cancer were included in this prospective comparative randomized study, in the period from January 2011 to September 2013. RESULTS: The patients were treated ... Read more

Concurrent radiotherapy and chemotherapy for locally advanced squamous cell carcinoma of the head and neck
BACKGROUND: concurrent chemoradiotherapy is the standard treatment for patients with advanced head and neck squamous cell carcinoma (HNSCC). The present study was carried to assess the feasibility and efficacy of low dose Gemcitabine as a radiosensitizer when used during radical therapeutic management of patients with locally advanced HNSCC. PATIENTS AND METHODS: Fifty-two patients with locally advanced HNSCC (stage III, 50%; ... Read more