Background: Nerve growth factor (NGF) and its high-affinity recep- tor, tyrosine kinase A (TrkA), are members of the neurotrophin family. NGF–TrkA are involved in murine hair morphogenesis and cycling. To date, their expression in human hair follicle (HF) is unknown. In this investigation, we hypothesize that NGF–TrkA proteins are expressed in the human scalp skin. Moreover, NGF–TrkA expression in HF ... إقراء المزيد

BACKGROUND Neurotrophin (NT)‐3 and its high‐affinity receptor tyrosine kinase C (Trk C) are essential for nervous system development. These members of the NT family are also involved in murine hair morphogenesis and cycling. However, their role in human hair follicle (HF) biology remains to be elucidated. OBJECTIVES To explore the role of NTs in human skin and HF biology. METHODS ... إقراء المزيد