essameldin_nada

Essameldin Abdelaziz Mohamed Ahmed Nada

Professor - Prof. of Dermatology,Venereology and Andrology

Faculty of medicine

Address: 8 Abou Bakr ElSedik Dokki Giza

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Publications Which contain the keyword: nuclear DNA


2018-10-17 13:06:17 Keywords Sperm, nuclear DNA, infertile men,
Increased sperm nuclear DNA damage in normozoospermic infertile men: a prospective study.
Conclusions: The results of this study indicated a significant incresae of SCSA-defined sperm nuclear DNA damage can be found in sperm from infertile men with normal standard semen parameters. Therefore, sperm DNA damage analysis may reveal a hidden abnormality of sperm DNA in infertile men who were previously classified as idiopathic based on apparantly normal standard semen parameters. Read more

2018-09-29 20:55:34 Keywords spermatozoa, Oxidative stress, nuclear DNA, male infertility,
Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility
OBJECTIVE: To examine the effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. DESIGN: Prospective study. SETTING: Infertility clinic at a tertiary care academic institution. PATIENT(S): Ninety-two infertile men with normal female partners. Sixteen fertile donors served as the control group. INTERVENTION(S): Standard semen analysis and assessment of levels ... Read more

2018-09-29 23:10:37 Keywords male infertility, nuclear DNA, Sperm,
Increased sperm nuclear DNA damage in normozoospermic infertile men: a prospective study.
OBJECTIVE: To evaluate levels of sperm nuclear DNA damage in infertile men with normal and abnormal standard semen parameters. DESIGN: Prospective study. SETTING: Male infertility clinic. PATIENT(S): Ninety-two men seeking infertility treatment and 16 fertile volunteers. INTERVENTION(S): Standard semen analysis was performed according to the World Health Organization guidelines. MAIN OUTCOME MEASURE(S): Sperm DNA damage was assessed by sperm chromatin ... Read more

Leukocytospermia is associated with increased   reactive oxygen species production by human spermatozoa.
OBJECTIVE: To investigate the role of increased seminal leukocytes in enhancing reactive oxygen species (ROS) production by human spermatozoa. DESIGN: A prospective study. SETTING: Male infertility clinic. PATIENT(S): Forty-eight infertile men. INTERVENTION(S): Standard semen analysis. Assessment of sperm nuclear DNA damage by sperm chromatin structure assay. Incubation of spermatozoa from nonleukocytospermic samples with blood neutrophils. MAIN OUTCOME MEASURE(S): Spontaneous and ... Read more