Seminal oxidative stress (OS) is an imbalance between levels of reactiveoxygen species (ROS) and total antioxidant capacity (TAC). Leukocytospermia is associated with excessive ROS production . The objective of this study was to examine TAC levels in infertile men with leukocytospermia. Semen specimens from 48 infertile men were examined according to the World Health Organization (WHO) guidelines (WHO,1999). Patient samples ... إقراء المزيد

Objective: The incidence of leukocytospermia ranges from 10% to 20%among infertile men. However, the role of leukocytospermia in the pathogenesis of male infertility remains highly controversial. Our study evaluated the relationship between leukocytospermia and standard semen parameters, levels of seminal reactive oxygen species (ROS), and the extent of sperm nuclear DNA damage. Design: Prospective study examining the relationship between leukocytospermia ... إقراء المزيد

OBJECTIVE: To investigate the role of increased seminal leukocytes in enhancing reactive oxygen species (ROS) production by human spermatozoa. DESIGN: A prospective study. SETTING: Male infertility clinic. PATIENT(S): Forty-eight infertile men. INTERVENTION(S): Standard semen analysis. Assessment of sperm nuclear DNA damage by sperm chromatin structure assay. Incubation of spermatozoa from nonleukocytospermic samples with blood neutrophils. MAIN OUTCOME MEASURE(S): Spontaneous and ... إقراء المزيد