Aim of the work
iming of presentation and surgical interference.
Patients and methods
University Hospital from July 2010 to April 2014. Necrotizing fasciitis (NF) was diagnosed clinically
and confirmed by intraoperative findings and routine postoperative histopathological
criteria in association to laboratory values e.g. total leucocytic count; band leucocytes percentage and
serum Na were recorded. According to these criteria, patients were classified into 2 groups: group A;
26 patients with objective crite
group).
Results:
espect to pain, tense edema, bullae, skin discoloration and crepitation (P= 0.04,
and 0.045 respectively). Elevated WBCs >15.4 ×10
of group B (
and 6.61% of group B (p=0.0001). Serum Na<1
and B respectively ((
A and the remaining 4 cases were subjected to major extremity amputations. The overall mortality
was 27% (7 pa
Among patients underlying early debridement within 12 hours of admission (n=17), there was 3
deaths (18%) versus 4 deaths out of 9 (44.4 %) were recorded in patients with de
0.05).
Conclusion:
easonable surgical outcome. In patients with clinical suspicious, laboratory parameters include
WBCs >15.4×10
helpful in early diagnosis
: To identify the pattern of clinical manifestation
: This prospective study was carried out in Surgery Department, Sohag
ria of NF and group B; 136 patients with criteria of non
There were a statistically significant differences between NF and non NF patients with
9 /L was found in 69% of group A patients and 8%
p=0.0001). Band form leucocytes percentage >10% was observed in 23.08 % of group A
35 mm/L was observed in 85% and10% of group A
p=0.0001). Repeated wide surgical debridement was done to 22 patients of group
tients) for group A (NF group) versus zero% for group B (non
NF is a potentially fatal disease. Early diagnosis remains the cornerstone in achieving
9/L , serum Na < 135 mmol/L and band form leucocytes percentage > 10% may be
and surgical outcome in relation to
study. Clinical
-NF (control
0.01, 0.032, 0.023,
-NF group) (p<0.0001).
layed operation (P<