Liver resection is the only curative treatment option for specific types of metastatic neoplasms.
Comparative studies on the clinical outcome of liver resection for colorectal liver metastasis (CRLM) and non CRLM
(N-CRLM) in Egypt remain inadequate.
Methods: Medical records of patients who underwent liver metastasectomy (April 2013-May 2017) at Sohag
University Hospital were reviewed. Patients were categorized according to the origin of the primary tumor into
CRLM versus N-CRLM. Demographic, clinical, operative and histopathologic data, postoperative surgical
complications and survival were analyzed.
Results: Twenty-six patients (15 CRLM and 11 N-CRLM) were retrospectively enrolled. N-CRLM group comprised
metastatic gall bladder (6), pancreas (2), breast (1) lung (1) and recurrent ovarian (1) cancers. There was no
significant difference regarding age or gender predilection. The complication score in CRLM group was not
significantly different compared with N-CRLM patients. However, subgroups of multivisceral resections showed
significantly higher grades of postoperative complications compared with sole liver resection in both groups. Elderly
patients (>70-year-old) exhibited high risk of morbidity compared with younger patients. Early post-operative
mortality within the first month was 7.7% (2 patients died, one per each group). After a mean follow up of 32 months,
the overall survival rate among patients with CRLM and N-CRLM was 75% and 64% respectively.
Conclusion: Liver resection for CRLM and N-CRLM can be safely accomplished. Multivisceral resection and
advanced age were associated with increased severity of postoperative complications irrespective of the location of