This lecture will discuss diseases that selectively affect the motor system.

The lecture will cover the following points:

INTRODUCTION

Classification¨

1- Pure upper motor  neuron diseases

¤Hereditary spastic paraplegia

¤1ry lateral sclerosis

2- Pure lower motor neuron diseases

¤Progressive muscular atrophy

¤Progressive bulbar palsy (hereditary bulbar palsy)

¤Spinal muscular atrophies.

¤Post-polio syndrome.

¤Post-irradiation syndrome.

3- Combined upper and lower motor neuron diseases

¤Amyotrophic lateral sclerosis (ALS).

 

Hereditary Spastic Paraplegia

Link 1: Clasp knife spasticity https://www.youtube.com/watch?v=re0WKy1zlY0

Primary lateral sclerosis

Inherited Spinal Muscular Atrophies

Amyotrophic Lateral Sclerosis (ALS)

         Link 2: Tongue fasciculations      https://www.youtube.com/watch?v=ano8mVMMseg

         Link 3: Arm fasciculations    https://www.youtube.com/watch?v=9Q0SfKfIcYc