ahmed.osman

Ahmed Mahmoud Osman KHEIMAR

Lecturer - Lecturer and PosDoc Associate of Poultry Diseases

Faculty of Veterinary Medicine

Address: Poultry Diseases department, Facultry of Veterinary Medicine, Sohag University, New Sohag City (El-Kawamel).

1

Like

I am a confident, enthusiastic and hardworking researcher in the area of poultry viral diseases and cancer biology. I am able to work independently or as apart of a larger team. I am often described as trustworthy and committed with strong communicative and organisational skills. I possess extensive knowledge in a plethora of Molecular Biology techniques, but also have an interest in other areas that involve poultry farming, vaccines and poultry disease diagnosis. I thrive best in an environment where I get a chance to be the creator of a good cooperation and synergy between multiple stakeholders. I got my master degree at 2011 where i firstly discovered that new avian influenza subtypes cirulating at chciken farms at Sohag University rather than H5 and H7. Then i moved to Germany to continue my passion towards poultry virology, where i started my PhD at institute of virology, Freie Universität Berlin. I obtained my PhD at 2017 and currently, im working as Lecturer of Poultry Diseases. 


2019-12-14 20:22:57 | Keywords
Imaging Mass Spectrometry and Proteome Analysis of Marek’s Disease Virus-Induced Tumors
The highly oncogenic alphaherpesvirus Marek’s disease virus (MDV) causes immense economic losses in the poultry industry. MDV induces a variety of symptoms in infected chickens, including neurological disorders and immunosuppression. Most notably, MDV induces transformation of lymphocytes, leading to T cell lymphomas in visceral organs with a mortality of up to 100%. While several factors involved in MDV tumorigenesis have ... Read more

2019-12-14 20:14:42 | Keywords Mareks disease virus- EBERs, ,
Epstein-Barr virus-encoded RNAs (EBERs) complement the loss of Herpesvirus telomerase RNA (vTR) in virus-induced tumor formation
Marek’s disease virus (MDV) is an alphaherpesvirus that causes fatal lymphomas in chickens and is used as a natural virus-host model for herpesvirus-induced tumorigenesis. MDV encodes a telomerase RNA subunit (vTR) that is crucial for efficient MDV-induced lymphoma formation; however, the mechanism is not completely understood. Similarly, Epstein Barr-virus (EBV) encodes two RNAs (EBER-1 and EBER-2) that are highly expressed ... Read more

2019-12-14 20:18:53 | Keywords meq, vTR, Tumors,
Viral factors involved in Marek’s disease virus (MDV) pathogenesis
Purpose of ReviewMarek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes various clinical symptomsincluding fatal lymphomas in chickens. The virus encodes several MDV-specific genes that play a major role in viral pathogen-esis. This review will focus on the recent advances in our understanding of how these viral factors contribute to pathogenesis andtumor formation.Recent FindingsSeveral viral factors involved in ... Read more

2019-12-14 20:20:11 | Keywords cellular telomerase RNA, Cance,
Overexpression of cellular telomerase RNA enhances virus-induced cancer formation
The telomerase RNA subunit (TR) is overexpressed in many tumors; however, the contribution of TR in cancer formation remains elusive. The most frequent clinically diagnosed cancer in the animal kingdom is caused by the highly oncogenic herpesvirus Marek’s disease virus (MDV). MDV encodes a TR (vTR) that plays an important role in virus-induced tumorigenesis and shares 88% sequence identity with ... Read more

2019-12-14 20:21:27 | Keywords vTR, Tumors,
The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs. Despite many years of research, the viral transcriptome in primary target cells of MDV remained unknown. In this study, we uncovered the transcriptional landscape of the very virulent ... Read more