Full Name	Ramy Kamal Amin Sayed
Email	ramy.kamal@vet.sohag.edu.eg
Gender	Male
birth date	1986-12-07
Faculty	Faculty of Veterinary Medicine
Degree	Lecturer
Address	Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Sohag University
Current Position	Lecturer of Veterinary Anatomy and Embryology

Phone	882374811
Mobile	0201025933699
Google Scholar URL	https://scholar.google.com.eg/citations?user=XcJq_gMAAAAJ&hl=en
Linked in URL
Research Gate	https://www.researchgate.net/profile/Ramy_Sayed6
EKP بنك المعرفة المصري

Personal Details

Title: Dr

First name: Ramy

Surname: Sayed

Middle names: Kamal Amin

Date of birth: 7^th December 1986

Marital status: Married with two kids

Website: https://scholar.google.com.eg/citations?user=XcJq_gMAAAAJ&hl=en

https://www.researchgate.net/profile/Ramy_Sayed6

http://www.scopus.com/authid/detail.url?authorId=57188992319

Email: ramy.kamal@vet.sohag.edu.eg & ramyelsheaby7@gmail.com

Mobile: 002-01025933699

Corresponding address in Egypt: Faculty of Veterinary Medicine, Sohag University, 82524, Sohag, Egypt.

 

Academic Employments

Current

Lecturer of Anatomy and Embryology, Anatomy and Embryology Department, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt

 

Previous

 2014-2016Visiting scholar at Biomedical Research Center, Institute of Biotechnology, Granada University, Spain

 2013-2014Assistant Lecturer of Anatomy and Embryology, Anatomy and Embryology Department, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt

 2010-2013Demonstrator of Anatomy and Embryology, Anatomy and Embryology Department, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt

 

Academic Qualifications

-       Ph.D. of Veterinary Medical Sciences (Animal Anatomy): Thesis title: "Morphology of skeletal and cardiac muscles in animals during aging". Faculty of Veterinary Medicine, Assiut University, Egypt. Through a joint supervision program with Granada University, Spain. Approved February 2017

Master of Veterinary Medical Sciences (Animal Anatomy): Thesis title: "Morphological studies on the roof of the oropharynx in turkey". Faculty of Veterinary Medicine, Assiut University, Egypt. Approved March 2013

Bachelor of Veterinary Medical Sciences: Faculty of Veterinary Medicine, Assiut University, Egypt. Approved June 2009, (General Grade Very Good With Honour, 84.10%)

 

Awards and Fellowships

-       Joint Ph.D. program fellowship sponsored by the Mission Sector, Egypt, and conducted at the Institute of Biotechnology, Biomedical Research Center, Granada University, Granada, Spain (24^th December 2014 – 24^th December 2016)

Scientific Excellence Award, Sohag University, 2018

 

Teaching Activities

Teaching anatomy of musculoskeletal system of animals for under graduate students of Sohag University since 2010

Teaching anatomy of fish and avian for under graduate students of Sohag University since 2010

Teaching general embryology for under graduate students of Sohag University since 2010

Teaching special embryology (development of different systems) for under graduate students of Sohag University since 2010

Teaching comparative anatomy of digestive, respiratory, cardiovascular, urogenital, nervous, and lymphatic systems for under graduate students of Sohag University since 2010

Teaching applied anatomy for under graduate students of Sohag University since 2010

Teaching advanced comparative anatomy of urogenital system for post graduate students of Sohag University since 2017

Teaching advanced comparative anatomy of digestive system for post graduate students of Sohag University since 2017

Supervision of the scientific thesis (M.V.Sc. and Ph.D.) in Assiut and Sohag Universities

Developing or updating new or existing veterinary anatomy and embryology courses

Developing new active teaching methods and techniques

 

Research Interests

Understanding morphological changes take place during aging, and studying the implication of NLRP3 inflammasome, mitochondrial and apoptotic pathways in this process, with investigating the role of antioxidants therapy

Studying the role of retinoid-related orphan receptors in various tissues' function

Investigating the gross and developmental anatomy of digestive and urogenital systems of mammals

Investigating the embryological development of skin of fishes and its associate structures

 

Training Courses

TOT (Training Of the Trainers) Course. IT training center, Sohag University, 11^th-19^th August 2018

High content imaging and analysis techniques for stem cell based toxicity studies + an Introduction to high resolution and super resolution imaging. Biomedical Research Center, Granada University, Granada, Spain, 13^th January 2016

University Administration. Faculty and Leadership Development Center (FLDC), Sohag University, 1^st-2^nd December 2014

Management of Research Team. FLDC, Sohag University, 1^st-3^rd November 2014

Web Publishing Using Front Page.nformation and Communication Technology Project (ICTP), Sohag University, ICTP, Sohag University

Strategic Planning. FLDC, Sohag University, 15^th-17^th December 2014

Quality Standards in Teaching FLDC, Sohag University, 7^th-9^th December 2014

International English Language Testing System (IELTS). British Council, 19^th March 2014

Basic Principles and Techniques on PCR. Molecular Biology Research Unit, Assiut University, 25^th-27^th November 2013

Teaching Preparation Course. Training Section of the General Administration of Graduate Studies and Research, Sohag University, 2^nd-12^th September

English Language Course. English For Specific Purposes Center, Sohag University, 13^th June 2012

International Computer Driving Licence. 26^th July 2011

The Use of Technology in Teaching. FLDC, Sohag University, 16^th-18^th January 2011

Statistical Analysis Using SPSS. ICTP, Sohag University, 26^th-30^th December 2010

Courses Specification and University Academic Standards. Development of Student's Assessment Systems Project (DSASP), Sohag University, 26^th-28^th December 2010

Graphics Adobe Photoshop. ICTP, Sohag University, 18^th-22^nd December 2010

Communication Skills in the Various Types of Education. FLDC, Sohag University, 21^st-23^rd November 2010

Scientific Publishing. FLDC, Sohag University, 26^th-28^th June 2010

Student Skills Development Program. Assiut University, 2008

 

Lab expertise

Animal handling and crossing

Dissection of different systems of animal's body

Isolation of pure DNA from tissues and applying genotype experiments

Performing phenotype studies through video-tracking open-field SMART test and control treadmill test

Isolation of pure RNA and applying RT-qPCR

Isolation of pure nuclear, cytosol, and mitochondrial fractions, measuring concentration of the protein and performing western blotting analysis

Isolation of pure intact mitochondria and measuring mitochondrial respiration parameters

Applying different histological, histochemical, immnuohistochemical, and immunofluorescence assays

Cutting sections by using Microtome, Cryostat, and Ultramicrotome

Semithin sections and transmission electron microscopy

Image J image processing software, and Graphpad prism software package

 

Memberships and social activities

Member of African Association of Veterinary Anatomists

Deputy Director of Quality Assurance Unit at my faculty

Member of Student's Assessment Systems Development Project

Member of Laboratories Committee

Sharing in the veterinary medical convoys

Participating in the volunteer works in my city and university

 

Language Skills

Arabic: Mother languag

English: Very good verbal, writing, and reading abilities. (IELTS, score 5.5)

Spanish: Fair verbal

 

Peer-Reviewed Publications

Sayed RKA, Mokhtar DM, Fernández-Ortiz M, Escames G, Acuña-Castroviejo D (2019). Retinoid-related orphan nuclear receptor alpha- (RORα-) deficient mice display morphological testicular defects. Laboratory Investigation, Nature Publishing Group. DOI: 1038/s41374-019-0299-5

Sayed RKA, Fernández-Ortiz M, Diaz-Casado ME, Aranda-Martínez P, Fernández-Martínez J, Guerra-Librero A, Escames G, López LC, Alsaadawy RM, Acuña-Castroviejo D (2019). Lack of NLRP3 inflammasome activation reduces age-dependent sarcopenia and mitochondrial dysfunction, favoring the prophylactic effect of melatonin. Journal of Gerontology: Series A Biological Sciences, Oxford Academic, DOI: 1093/gerona/glz079

Hidalgo-Gutiérrez A, Barriocanal-Casado E, Bakkali M, Diaz-Casado ME, Sanchez-Maldonado L, Romero M, Sayed R, Prehn C, Escames G, Duarte J, Acuña-Castroviejo D, López LC (2019). β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice. EMBO Molecular Medicine, Wiely, 11:e9466. DOI:15252/emmm.201809466

Sayed RK, Fernández-Ortiz M, Diaz-Casado ME, Rusanova I, Rahim I, Escames G, López LC, Mokhtar DM, Acuña-Castroviejo D (2018). The protective effect of melatonin against age-associated sarcopenia-dependent tubular aggregates formation, lactate depletion and mitochondrial changes.   Journal of Gerontology: Series A Biological Sciences, Oxford Academic, 73(10):1330-1338. DOI:1093/gerona/gly059

Mousa MA, Sayed RK, Osman AS, Sayed HH (2018). Assessment of date palm pollen supplementation on productivity, digestibility, immune response, and intestinal and hepatic morphology of Egyptian fayoumi laying Hens. Journal of Dairy, Veterinary & Animal Research, 7(4):133-138.

EL Shoukary RD, Sayed RK, Hassan RI (2018). Behavioral, hepato-morphological, and biochemical studies on the possible protective effect of black seed and water bath against change-mediated heat stress on pigeon. The Journal of Basic and Applied Zoology, 79:23. https://doi.org/10.1186/s41936-018-0035-5

Díaz-Casado ME, Rusanova I, Aranda P, Fernández-Ortiz M, Sayed RK, Fernández-Gil BI, Hidalgo-Gutiérrez A, Escames G, López LC, Acuña-Castroviejo D (2018). In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy. Zebrafish, Mary Ann Liebert, Inc. 15(1):15-26. DOI:1089/zeb.2017.1479

Acuña-Castroviejo D, Rahim I, Acuña-Fernández C, Fernández-Ortiz M, Solera-Marín J, Sayed RK, Díaz-Casado ME, Rusanova I, López LC, Escames G (2017). Melatonin, clock genes and mitochondria in sepsis. Cellular and Molecular Life Sciences, SpringerLink, 74(21):3965-3987. DOI:10.1007/s00018-017-2610-1

Fernández-Gil B, Moneim AE, Ortiz F, Shen YQ, Soto-Mercado V, Mendivil-Perez M, Guerra-Librero A, Acuña-Castroviejo D, Molina-Navarro MM, Garcia-Verdugo JM, Sayed RK, Florida J, Luna JD, López LC, Escames G (2017). Melatonin protects rats from radiotherapy-induced small intestine toxicity. PLoS One, 12(4):e0174474. DOI:1371/journal.pone.0174474

Rahim I, Djerdjouri B, Sayed RK, Fernández-Ortiz M, Fernández-Gil B, Hidalgo-Gutiérrez A, López LC, Escames G, Reiter RJ, Acuña-Castroviejo D (2017). Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis. Journal of Pineal Research, Wiely, 63(1). DOI:1111/jpi.12410

Leonardo-Mendonça RC, Ocaña-Wilhelmi J, de Haro T, de Teresa-Galván C, Guerra-Hernández E, Rusanova I, Fernández-Ortiz M, Sayed RK, Escames G, Acuña-Castroviejo D (2017). The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes. Applied Physiology, Nutrition, and Metabolism, 42(7):700-707. DOI:1139/apnm-2016-0677

Escames G, Fernández-Gil BI, Guerra-Librero A, Shen Y, García-López S, Florido J, Sayed R, Acuña-Castroviejo D, Esposito J (2017). PO-089: Melatonin enhances the toxicity of radio-and chemotherapy in head and neck cancer cells. Radiotherapy and Oncology, 122: 43. https://doi.org/10.1016/S0167-8140(17)30223-2

Escames G, Guerra-Librero A, Shen Y, Florido J, Sayed R, Molina-Navarro M, Gonzalez-Diez M, Acuña-Castroviejo D, Exposito J (2017). PO-090: Oncostatic effect of melatonin in head and neck cancer: role of mitochondrial function. Radiotherapy and Oncology, 122:43-44. https://doi.org/10.1016/S0167-8140(17)30224-4

Sayed RK, Abdalla KEH, Saleh AM, Ahmed AK (2017). Macro and Microanatomical Studies on the Choanal Slit of Turkey (Meleagris gallopavo). Journal of Advanced Veterinary Research, 7(3):75-80

Luna-Sánchez M, Hidalgo-Gutiérrez A, Hildebrandt TM, Chaves-Serrano J, Barriocanal-Casado E, Santos-Fandila Á, Romero M, Sayed RK, Duarte J, Prokisch H, Schuelke M, Distelmaier F, Escames G, Acuña-Castroviejo D, López LC (2017). CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome. EMBO Molecular Medecine, 9(1):78-95. DOI:15252/emmm.201606345

Sayed RK, Fernández-Ortiz M, Rahim I, Acuña-Castroviejo D (2016). Oral communication: NLRP3 inflammasome affects mitochondrial morphology in skeletal muscle of mice. Physiology and Biochemistry, 72:S35

Fernández-Ortiz M, Sayed RK, Pozo JA, Martínez PA, Acuña-Castroviejo D (2016). Aging and Sarcopenia. Role of the innate immunity and melatonin therapy. Physiology and Biochemistry, 72:S34.

Sayed RK, de Leonardis EC, Gueerrero-Martínez JA, Rahim I, Mokhtar DE, Saleh AM, Abdalla KE, Pozo MJ, Escames G, López LC, Acuña-Castroviejo D (2016). Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice. Experimental Gerontology, Elsevier, 83:22-30. DOI:10.1016/j.exger.2016.07.007

Díaz-Casado ME, Lima E, García JA, Doerrier C, Aranda P, Sayed RK, Guerra-Librero A, Escames G, López LC, Acuña-Castroviejo D (2016). Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network. Journal of Pineal Research, Wiely, 61(1):96-107. DOI:1111/jpi.12332

Sayed RK, Saleh AM, Ahmed AK, Abdalla KEH (2016). Gross Anatomical, Light and Scanning Electron Microscopic Studies on the Pharyngeal Roof of Turkey (Meleagris gallopavo): Comparative Study. Journal of Advanced Veterinary Research, 6(4):112-117

Sayed RK, Abdalla KEH, Ahmed AK, Saleh AM (2016). Palate of Turkey (Meleagris gallopavo): Gross Anatomical, Light and Scanning Electron Microscopical Study. Journal of Advanced Veterinary Research, 6(3):81-88

Sayed RK, Abdalla KEH, Ahmed AK, Saleh AM (2014). Morphological Studies on the Upper Beak of Turkey (Meleagris gallopavo). Journal of Advanced Veterinary Research, 4(4):154-160.

 

Presentations, and Conference Papers

Melatonin enhances the toxicity of radio-and chemotherapy in head and neck cancer cells. G. Escames, B.I. Fernández-Gil, A. Guerra-Librero, Y. Shen, S. García-López, J. Florido, Sayed, D. Acuña-Castroviejo, J. Esposito. Poster, 6^th ICHNO International Conference on Innovative Approaches in Head and Neck Oncology, March 16-18^th, 2017, Barcelona, Spain

Oncostatic effect of melatonin in head and neck cancer: role of mitochondrial function. G. Escames, A. Guerra-Librero, Y. Shen, J. Florido, Sayed, M. Molina-Navarro, M. Gonzalez-Diez, D. Acuña-Castroviejo, J. Exposito. Poster, 6^th ICHNO International Conference on Innovative Approaches in Head and Neck Oncology, March 16-18^th, 2017, Barcelona, Spain

Influencia del inflamasome NLRP3 sobre la morfologia del musculo esqueletico de raton. K. Sayed, M. Fernández-Ortiz, I. Rusanova, G. Escames, D. Acuña-Castroviejo. Poster, Revista Española de Medicina Geriátrica, November 10^th-12^th, 2016, Santander, Spain

Efecto del inflamasoma NLRP3 sobre la sarcopenia y terapia con melatonina. M. Fernández-Ortiz, K. Sayed, I. Rahim, G. Escames, D. Acuña-Castroviejo. Poster, Revista Española de Medicina Geriátrica, November 10^th-12^th, 2016, Santander, Spain

Metabolic switch produced by melatonin in head and neck cancer cells. A. Guerra-Librero, BI. Fernandez-Gil, S. Garcia-Lopez, YQ Shen, J. Florido, Sayed, MM. Molina-Navarro, JM Garcia-Verdugo, M. Gonzalez-Diez, LC. Lopez, D. Acuña-Castroviejo, I. Tovar, G. Escames. Poster, Translational Research in cancer cell metabolism, October 2016, Bilbao, Spain

NLRP3 inflammasome affects mitochondrial morphology in skeletal muscle of mice. Ramy K Sayed, Marisol Fernández Ortiz, Ibtissem Rahim, Darío Acuña-Castroviejo. Oral communication, XXXVIII Congress of the Spanish Society of Physiological Sciences (SECF), September 13^th-16^th, 2016, Zaragoza, Spain

Aging and Sarcopenia. Role of the innate immunity and melatonin therapy. Marisol Fernández Ortiz, Ramy K Sayed, Juan Ángel Rodríguez Pozo, Paula Aranda Martínez, Darío Acuña-Castroviejo. Oral communication, XXXVIII Congress of the Spanish Society of Physiological Sciences (SECF), September 13^th-16^th, 2016, Zaragoza, Spain

Melatonin at high concentration enhances the toxicity of radio- and chemotherapy in tongue cancer cells. BI. Fernández-Gil, YQ. Shen, A. Guerra-Librero, J. Florido, M.A. Mendivil-Pérez, V.M. Soto, Ramy K Sayed, M. González-Díez, D. Acuña-Castroviejo, G. Escames. Poster, XI Meeting of the Spanish Group for Free Radical Research (GEIRLI), September 13^th‐14^th, 2016, Granada, Spain

La conexión parkin/PINK1/DJ-1/MUL1, diana molecular de la melatonina que explica sus propiedades antiparkinsonianas. Darío Acuña-Castroviejo, Elena Díaz-Casado, Paula Aranda, Marisol Fernández-Ortiz, Ramy KA Sayed. Presentation Session, XI Meeting of the Spanish Group for Free Radical Research (GEIRLI), September 13^th‐14^th, 2016, Granada, Spain

Estudio de microRNAs en suero como predictores y marcadores de envejecimiento y fragilidad en humanos. Iryna Rusanova, Ramy KA Sayed, Marisol Fernández-Ortiz, Darío Acuña-Castroviejo. Poster, XI Meeting of the Spanish Group for Free Radical Research (GEIRLI), September 13^th‐14^th, 2016, Granada, Spain

37^th Scientific conference of The Egyptian Society of Histology and Cytology, December 12^th, 2013, Histology and Biology Dept., Faculty of Medicine, Alexandria University, Egypt