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حسام الدين عبدالغني حسين

استاذ -

كلية العلوم

العنوان: جامعة سوهاج - كلية العلوم - قسم الكيمياء

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حسام الدين عبدالغني حسين

الاستاذ بقسم الكيمياء كلية العلوم


2018-10-31 16:02:23
For students
DEAR STUDENTS PLEASE FOLLOW UP MY WEBPAGE DURING THE SEMESTER TIME FOR THE NEW COURSE UPDATES, QUIZZES AND TASKS إقراء المزيد

2018-10-31 16:38:24 | الكلمات المفتاحية phase transfer catalysis, thienopyridines, Pyridines,
Synthesis of Novel Fused Heterocycles Based on 6-Amino-4-phenyl-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitrile
Under phase transfer catalysis conditions, 6‐amino‐4‐phenyl‐2‐thioxo‐1,2‐dihydropyridine‐3,5‐dicarbonitrile (1) was allowed to react with halo compounds, acrylonitrile, chloroacetyl chloride, ethyl cyanoacetate, formamide, triethylorthoformate, or formic acid to give new derivatives of fused pyridines 2–22, respectively. Acetylation of compound 1 using acetic anhydride afforded product 23, which in turn underwent intramolecular cyclization in pyridine to give the corresponding pyrido[2,3‐_d_]pyrimidine 24. إقراء المزيد

2018-10-31 16:47:41 | الكلمات المفتاحية pyrrazole;, pyrimidine;, pyridine;, PASS INET, fused pyridine, phase transfer catalysis, pyrrole,
Synthesis of Some New F used P yridines and Prediction their Biological Activity via PASS INET
A new series of fused heterocyclic compounds containing pyridine moieties were prepared via the reaction of 2-amino-6-(methylthio)-4-phenylpyridine-3,5-dicarbonitrile with some halo reagents, active methylenes, acetic anhydride, phenylisothiocyanate, hydrazine hydrate or thioacetamide. Accompanied with Predictions of the activity spectra of some selected compounds using PASS INET.at Pa > 70%, showing high probability of Atherosclerosis treatment, Antineoplastic, DNA intercalator, Protein kinase inhibitor and ... إقراء المزيد