Abstract Background Osteoarthritis (OA) is a common joint disorder, with the knee being one of the most frequently involved sites. Knee OA causes pain and stiffness and can lead to considerable disability and consequently to a reduced quality of life (Wideman et al. 2014). The level of radiographic knee OA is, at most, moderately associated with the level of pain. ... Read more

Abstract—Ankle joint evaluation is underestimated in many clinical and sonographic scores used for evaluation and follow-up of rheumatoid arthritis (RA) patients. Agreement on examination parameters is poor among sonographic scores that include the ankle joint. More effort is needed to detect the value of ankle joint examination in RA and assessment of ultrasonographic signs according to frequency, disease duration and ... Read more

Ultrasound (US) is one of the most widely used tools for diagnosis and evaluation of carpal tunnel syndrome (CTS). US achievement is comparable to the gold standard electrophysiological studies. Depth of the carpal tunnel is a promising, relatively new sonographic parameter used for assessment of the median nerve. Previously it was evaluated in cadavers, normal individuals and in idiopathic carpal ... Read more

Background: Diabetes mellitus (DM) is a chronic metabolic disease with high morbidity and mortality (1). Over than 7.8 million in Egypt suffer from DM in 2015 (2). Most of DM morbidity and Mortality is related to micro and macro vascular complications. However, it is also associated with musculoskeletal (MSK) disorders of the hand that can be very debilitating and significantly ... Read more

Background Rheumatoid arthritis (RA) is one of the commonest autoimmune diseases. It affects about 1% of the population worldwide (1). The prevalence of RA varies widely between different countries (2). Not only the prevalence of the disease which differs among different continents, races, ages and socioeconomic levels but also the disease pattern. Studies explaining the epidemiology of RA in Egypt ... Read more

Objective. To evaluate the effectiveness of spironolactone as a treatment for osteoarthritis (OA)-related knee effusion in comparison to ibuprofen, cold compresses, and placebo. Methods. This study was carried out on 200 patients, aged 40 years or older, attending the outpatient clinic of the Rheumatology Department of Sohag University Hospital with unilateral knee effusion related to OA based on clinical examination, ... Read more

Abstract—The objective of the work described here was to evaluate the depth of the carpal tunnel (DCT) in patients with idiopathic carpal tunnel syndrome (CTS) and healthy volunteers by ultrasonography (US), through measurement of the distance from the flexor retinaculum to the surface of the capitate bone at the carpal tunnel outlet, and compare it with other ultrasonographic and electrophysiologic ... Read more

The objective of this work was to evaluate the sonographic features of gouty arthritis and correlate findings with disease duration. The study was conducted on 100 patients in ambulatory care aged $40 y. Inclusion criteria included mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal (MTP) joint and no known history of gout. A complete medical history ... Read more

Amyloid deposition in multiple myeloma (MM) may lead to an arthropathy resembling rheumatoid arthritis (RA). Since a systematic description of its natural history is lacking, we have performed a systematic analysis of all published cases. Literature review featuring backward and forward database searches and direct inspection of reference lists. Inclusion criteria were as follows: publication between 1931 and 2012, diagnosis ... Read more

Objectives To describe histological, immunohistochemical and ultrastructural features of synovial biopsies of amyloid arthropathy associated with multiple myeloma (MM). Methods Synovial biopsies from affected joints of two patients with MM and amyloid arthropathy were examined with light and electron microscopy, and immunohistochemically for expression of CD3, CD8, CD20, CD38, CD68, Ki-67 and vWF. Results were compared to values from osteoarthritis ... Read more