ABSTRACT BACK GROUND/AIMS To analyse different parameters of the macula, disc and their vascular affection using optical coherence tomography (OCT) and angiography (OCT-A) in patients with multiple sclerosis (MS) correlating these changes to PARP-1 gene expression in blood. METHODS This cross-sectional study included 80 eyes of the clinically diagnosed relapsing-remitting phenotype of MS. The study included three groups; group (A) ... Read more

Parkinson’s disease is one of the neurodegenerative disorders that is caused by genetic and environmental factors or interaction between them. Solute carrier family 41 member 1 within the PARK16 locus has been reported to be associated with Parkinson’s disease. Cognitive impairment is one of the non-motor symptoms that is considered a challenge in Parkinson’s disease patients. This study aimed to ... Read more

Cognitive dysfunction is one of the major contributors to the burden of epilepsy. It can significantly disrupt intellectual development in children and functional status and quality of life in adults. There is major evidence confirms that cognitive impairment can appear or worsen with early and chronic progressive neurologic changes in epilepsy. It has been increasingly accepted that comorbidity does not ... Read more

Sleep is a highly coordinated physiologic state, which is essential for functional integrity of the neurons and brain. It is crucial for survival. Non rapid eye movement sleep (NREM) vagal dominance enables neural/cardiovascular axis to regenerate homeostasis after periods of stress or fatigue during wakefulness. Any reasons of sleep interruption or deprivation like periodic limb movements during sleep (PLMS), insomnia, ... Read more

ABSTRACT The fast invasion of coronavirus pandemic (COVID-19) attributed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is becoming international major health problem. It has been defined as a pandemic by the World Health Organization (WHO) in March this year. Nearly all COVID-19 patients have dyspnea as the most prominent symptom. Neurologic manifestations may also present such as anosmia, headache, ... Read more