elsayed_ali

Elsayed Mostafa Ali Hassan

Assistant Professor - قائم بعمل رئيس قسم الأورام و الطب النووي

Faculty of medicine

Address: مستشفي سوهاج الجامعي- قسم علاج الأورام و الطب النووي

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Study of Neuropilin-1/Cd304 Expression in Leukemogenesis

2018 | Keywords Acute myeloid le, Neuropilin-1,
Study of Neuropilin-1/Cd304 Expression in Leukemogenesis
Abstract Neuropilins are transmembrane glycoproteins that act as receptors for vascular endothelial growth factors (VEGF) and are involved in the process of tumor angiogenesis. Its importance in hematological malignancies such as acute leukemia (AL) remains to be elucidated. The aim of this study was to evaluate the significance of neuropilin-1 expression in acute myeloid leukemia (AML) and acute lymphocytic leukemia ... Read more

Characteristics of escape mutations from occult hepatitis B virus infected patients with hematological malignancies in South Egypt

2017 | Keywords Occult hepatitis B infection;,
Characteristics of escape mutations from occult hepatitis B virus infected patients with hematological malignancies in South Egypt
Abstract AIM To investigate the prevalence and virological characteristics of occult hepatitis B virus (HBV) infections in patients with hematological malignancies in South Egypt. METHODS Serum samples were collected from 165 patients with hematological malignancies to monitor titers of HBV DNA, hepatitis B surface antigen (HBsAg), and antibodies to HBV core (anti-HBc) and surface antigens. Serum samples negative for HBsAg ... Read more

Outcome of continuous infusion of low dose gemcitabine in locally advanced and metastatic pancreatic carcinoma

2016 | Keywords pancreatic carcinoma,
Outcome of continuous infusion of low dose gemcitabine in locally advanced and metastatic pancreatic carcinoma
Introduction: This study is to evaluate the outcome of patients with locally advanced and metastatic pancreatic cancer treated with continuous infusion of low dose gemcitabine. Patients were recruited from oncology outpatient clinic, Sohag University and South Egypt Cancer Institute. Methods: From December 2013, to October 2014, 26 patients with locally advanced or metastatic pancreatic cancer (stage III, stage IV) histopathologically ... Read more

Comparative study of Gemcitabine versus Cisplatin concurrent with radiotherapy for locally advanced head and neck cancer

2014 | Keywords Cisplatin, gemcitabine, Chemotherapy, radiotherapy, Head and Neck,
Comparative study of Gemcitabine versus Cisplatin concurrent with radiotherapy for locally advanced head and neck cancer
ABSTRACT PURPOSE: In our study we compared low-dose gemcitabine-based chemoradiotherapy with cisplatin-based chemoradiotherapy as regards response rate, survival and toxicity profile in locally advanced head and neck cancer. METHODOLOGY: sixty patients with locally advanced head and neck cancer were included in this prospective comparative randomized study, in the period from January 2011 to September 2013. RESULTS: The patients were treated ... Read more

Correlation of Breast Cancer Subtypes Based on ER, PR and HER2 Expression with Axillary Lymph Node Status

2014 | Keywords Her-2, PR, ER, Breast Carcinoma, Axillary Lymph Node Status, Breast Cancer Subtypes,
Correlation of Breast Cancer Subtypes Based on ER, PR and HER2 Expression with Axillary Lymph Node Status
ABSTRACT BACKGROUND:Lymph node metastasis is the most important prognostic factor in breast cancer patients. The present study was carried out to evaluate the association between ER, PR and HER-2/neu expression status, separately and in combinations with axillary lymph node involvement. PATIENTS AND METHODS: Two hundred and fifty eight breast cancer patients treated with modified radical mastectomy with axillary lymph node ... Read more

Transcatheter administration of buffered Lidocaine for pain relief due to transarterial chemoembolization for HCC

2014 | Keywords Buffered Lidocaine; Transarter,
Transcatheter administration of buffered Lidocaine for pain relief due to transarterial chemoembolization for HCC
Abstract PURPOSE: To assess the efficacy of intra-arterial Lidocaine on post-procedural pain and on length of hospital stay in hepatocellular carcinoma (HCC) patients undergoing chemoembolization. MATERIALS AND METHODS: Thirty-nine transarterial chemoembolization (TACE) procedures were carried out for 21 consecutive patients (19M, 2F, age range 52–78).This is a prospective randomized controlled study. Lidocaine was used in 20 TACE and normal saline ... Read more

Post-mastectomy Hypofractionation Radiotherapy in Breast Cancer Patients

2014 | Keywords Breast Cancer; Hypofractionati,
Post-mastectomy Hypofractionation Radiotherapy in Breast Cancer Patients
Abstract Background: Post-mastectomy radiotherapy reduces loco-regional recurrence in women with operable breast cancer and improves survival. Conventional fractionated radiotherapy has been limited by patient’s compliance, travelling, unplanned interruption and others. Hypofractionated schedule would be more appealing and convenient. The present study was carried out to compare overall survival, disease free survival, loco regional control, and treatment toxicities, in patients treated ... Read more

TOTAL/NEAR-TOTAL VERSUS HEMI-THYROIDECTOMY FOR LOW-RISK WELL DIFFERENTIATED THYROID CANCER: A RETROSPECTIVE STUDY

2013 | Keywords Conservative thyroidectomy, Thyroid surgery, Thyroid neoplasms.,
TOTAL/NEAR-TOTAL VERSUS HEMI-THYROIDECTOMY FOR LOW-RISK WELL DIFFERENTIATED THYROID CANCER: A RETROSPECTIVE STUDY
ABSTRACT BACKGROUND: There is a controversy regarding management of low- risk well differentiated thyroid carcinoma (WDTC) between total/ near total thyroidectomy (TT) and hemi- thyroidectomy (HT) due to the excellent prognosis and the indolent course of the disease. This study aimed to review the outcome of TT in comparison with HT in management of low- risk WDTC. PATIENTS AND METHODS: ... Read more

Upper Egypt experience in bladder preservation using concurrent chemoradiotherapy

2013 | Keywords Bladder preservation, Concurrent chemoradiotherapy, Bladder cancer,
Upper Egypt experience in bladder preservation using concurrent chemoradiotherapy
OBJECTIVE: To share our experience in bladder preservation in Upper Egypt, Assiut and Sohag Universities, using different treatment protocols. In Sohag study patients with operable muscle invasive bladder cancer were included and underwent transurethral resection followed by radiochemotherapy (5- fluorouracil and Cisplatin) for bladder preservation. In Assiut study after maximum safe resection of bladder tumor, patients received combined chemo-radiotherapy, 60 ... Read more

Incidence and characteristics of HBV reactivation in hematological malignant patients in south Egypt

2013 | Keywords Hepatitis B virus; Occult infection; Rea,
Incidence and characteristics of HBV reactivation in hematological malignant patients in south Egypt
ABSTRACT AIM: To investigate characteristics of hepatitis B virus (HBV) implicated in HBV reactivation in patients with hematological malignancies receiving immunosuppressive therapy. METHODS: Serum samples were collected from 53 patients with hematological malignancies negative for hepatitis B surface antigen (HBsAg) before the start of and throughout the chemotherapy course. HBV reactivation was diagnosed when the HBsAg status changed from negative ... Read more