mamdouh_esmat

Mamdouh Mohamed Esmat Abdelwahed

Professor - Professor of Medical microbiology and immunology

Faculty of medicine

Address: Sohag Faculty of medicine- Medical microbiology and immunology depatment

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2017 | Keywords Gene polymorphism, hepatitis C,
Interleukin-10 and Interferon Gamma Gene Polymorphisms and Hepatitis C Virus–Related Liver Cirrhosis Risk
The aim of the study was to evaluate the association between the gene polymorphisms in interleukin-10 (IL-10) and interferon gamma (IFN-g) genes with susceptibility and severity of hepatitis C virus (HCV) infection among Egyptian patients. Interleukin-10 -592 A/C, -1082 G/A and IFN-g +874 T/A genotypes were determined in 100 chronic HCV patients and 50 healthy controls using restriction fragment length ... Read more

2017 | Keywords MDR, Red Plague, Tigecycline,
Resistant Gram-negative bacilli (Red Plague) from ICU in Sohag University Hospital
Background: Gram-negative bacteria; such as Escherichia, Klebsiella, Enterobacter, proteus, Pseudomonas and Acinetobacter, are common human pathogens. Now, it is difficult to treat these infections by most of the available antibiotics due to emergence of multidrug resistant Gram-negative bacilli or Red Plague. Objectives: This work aims to identify the rate of resistant gram negative bacteria in Sohag University hospital. Methodology: The ... Read more

Quinolone Resistance among Extended-Spectrum β -Lactamases Producing Klebsiella pneumoniae in Sohag University Hospital, Upper Egypt
Background: Extended-spectrum β-lactamases (ESBLs) production is the major resistance mechanism to β-lactam antibiotics in Enterobacteriaceae. Moreover, the emergence of quinolone resistance in ESBLs-producing isolates had become a global threat for treatment of infections caused by these bacteria. Objectives: We investigated the association between ESBLs production and quinolone resistance in Klebsiella pneumoniae isolates. Methodology: A total of 148 isolates of K. ... Read more

2016 | Keywords Herpes simplex virus, (ELISA), (PCR),
Effective Use of Enzyme Linked Immunosorbent Assay (ELISA) and Polymerase Chain Reaction (PCR) for Detection of Herpes Simplex Virus Infection in Pregnant Females at Sohag University Hospital
Background: Infection with herpes simplex virus is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn, which can lead to death or long-term disabilities. Objectives: The aim of our study was to detect the seroprevalence of Herpes ... Read more

2016 | Keywords TTIs,
STUDY OF THE PREVALENCE OF TREPONEMA PALLIDUM CAUSED SYPHILIS IN SUHAG GOVERNORATE THROUGH BLOOD DONOR’S REGIONAL CENTER FOR THE NATIONAL BLOOD TRANSFUSION SERVICES
ABSTRACT Treponema pallidum is a motile Gram-negative bacterium causing syphilis. Syphilis is one of the known sexually transmitted infections (STIs) and transfusion transmitted infections (TTIs). Blood samples from 16,000 Egyptian blood donors attending all blood banks in Suhag governorate during the period between January 2015 to December 2015 were screened for markers of infection with hepatitis B virus (HBV), hepatitis ... Read more

2015 | Keywords Atherosclerosis, Chlamydophila,
Relationship between Chlamydophila Pneumoniae and Atherosclerosis
The present work to evaluate whether there is a significant relationship between atherosclerosis and Chlamydophila Pneumoniae (C. pneumoniae) infection by using the Enzyme Linked Immunosorbent Assay (ELISA) techniques to detect the antibodies, and polymerase chain reaction (PCR) to detect the microbial DNA. Case-control study was carried out on atheromatous plaque and serum samples obtained from 74 patients with peripheral arterial ... Read more

Species Identification and Antifungal Susceptibility Profile of Candida Isolates from ICU Patients in Sohag University Hospital, Upper Egypt
Background: Candida species are among the most common fungal pathogens in ICU patients. Candida albicans was the predominant species, but a shift toward non-albicans Candida species has been recently observed. Objectives: To detect the prevalence of different Candida species and determine their antifungal susceptibility profile in ICU patients using phenotypic methods, the Vitek 2 system compared with CHROMagar Candida agar ... Read more

Occult Hepatitis B Virus Infection among Egyptian Hepatitis C Virus Seropositive and Seronegative Hemodialysis Patients in Sohag Government, Upper Egypt
Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) Infections are important and common causes of liver disease in end-stage renal failure (ESRF) in patients on haemodialysis (HD). HBV is less endemic than HCV in Egypt (ranges from 2%–7%). Although, the prevalence of HBV in haemodialysis patients has decreased significantly due to HBV vaccine and screening of blood donors, ... Read more

2012 | Keywords ACCP, rheumatoid factor.rheuma,
Anti-Cyclic Citrullinated Peptide (ACCP) Antibody versus Rheumatoid Factor (RF) For Diagnosis of Rheumatoid Arthritis
Introduction: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by chronic joint inflammation and extra-articular manifestations culminating in permanent disability without early therapeutic interventions. Early accurate diagnosis and therefore treatment of rheumatoid arthritis (RA) has become increasingly important. Aim of the Work: To compare the diagnostic power of anticyclic citrullinated peptide (ACCP) antibody to rheumatoid factor (RF) in RA ... Read more

2012 | Keywords procalcitonin, CRP, diagnosis,
Procalcitonin or C-reactive protein or both for diagnosis of neonatal sepsis?
Background: Early recognition and diagnosis of neonatal sepsis is difficult because of the variable and non-specific clinical presentation of this condition. It is extremely important to make an early diagnosis of neonatal sepsis for the prompt institution of anti-microbial therapy, which improves outcomes. Aims: The aim of this study was to determine the role of Procalcitonin (PCT) and C-reactive protein ... Read more

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