Background: Escherichia coli (E. coli) are the most common etiological agents of hospital acquired and community acquired urinary tract infections (UTIs) and the incidence of antibiotic resistant strains has been steadily increasing over the past few years resulting in limitation of therapeutic options. Our objectives were to investigate the prevalence and molecular characterization of extended spectrum β- lactamases (ESBLs) producing ... إقراء المزيد

Psoriasis is one of the most common chronic, inflammatory, T-cell-mediated autoimmune diseases. Narrow-band UVB (NB-UVB) therapy is widely used in the treatment of psoriasis; however, its mechanism of action is still not well understood. The objective of this study was to investigate the circulating T-lymphocyte subpopulations in psoriasis patients before and after NB-UVB, to get insights into the mechanism of ... إقراء المزيد

Psoriasis is one of the most common chronic, inflammatory, T-cell-mediated autoimmune diseases. Narrow-band UVB (NB-UVB) therapy is widely used in the treatment of psoriasis; however, its mechanism of action is still not well understood. The objective of this study was to investigate the circulating T-lymphocyte subpopulations in psoriasis patients before and after NB-UVB, to get insights into the mechanism of ... إقراء المزيد

Abstract: Chronic obstructive pulmonary disease (COPD) is a treatable and preventable disease state, characterized by progressive airflow limitation that is not fully reversible. In the present study; 101 COPD patients and 52 agematched healthy nonsmokers (HNS) control subjects were recruited and their pulmonary functions were assessed. The frequencies of CD3+ T, CD4+ T, CD8+ T, B, NK, NKT-like cells and ... إقراء المزيد

Abstract: Background: Inappropriate activation or blockage of inhibition of the complement system could cause tissue damage in autoimmune diseases particularly rheumatoid arthritis (RA). CD55 and CD59 are proteins with complement regulatory (Creg) properties that ensure cell and tissue integrity when this system is activated. Objective: The aim of this study was to evaluate the expression of CD55 and CD59 complement ... إقراء المزيد

Rheumatoid arthritis (RA) is a chronic autoimmune systemic disorder characterized by inflammatory responses mainly affecting the synovial joints. Interleukin-23 (IL-23) is a heterodimeric pro-inflammatory cytokine secreted by activated dendritic cells and activated macrophages. IL-23 is the key cytokine controlling inflammation in peripheral tissues leading to the development of autoimmune diseases. The objective of our study was to determine the relationship ... إقراء المزيد