Melatonin enhances the toxicity of radio-and chemotherapy in head and neck cancer cells
After reported a melatonin’s gel that protects normal cells from oral mucositis induced by radio- or chemotherapy, we wondered about how melatonin affects tumoral cells. It is well known that both radio- and chemotherapy act at different intracellular levels such as nucleus, membranes and mitochondria. On the other hand, mitochondrion is the main melatonin target. So we evaluated here whether ... Read more