Synthesis of 5-Cyano-2-Carbethoxythieno [2,3-b] thiophenyl-3, 4- Di- isothiocyanates and Its Utility IN Heterocyclic Synthesis Under Phase Transfer Catalytic Technique
Regarding to the importance of thieno[2,3-b]thiophens and isothiocyanaetes reactiveties in the physical, chemical and pharmaceutical fields, this study has been undertaken to prepare the target compound 5-cyano-2-carbethoxythieno[2,3-b] thiophenyl-3,4-diisothiocyanates via a safe method. The formed isothio cyanates derivative was reacted with aromatic amines, acid hydrazied and some active methylene groups, followed by cyclization reaction for the formed intermediates to give new ... Read more