Immunophenotypic and prognostic features of BCR-ABL genes fusion, amplification, and deletion in acute lymphoblastic leukemia by extrasignal FISH
Acute lymphoblastic leukemia (ALL) is a clonal malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells of the marrow (JIANG ET AL., 2010). Cytogenetic abnormalities are independent prognostic variables for predicting the outcome of adult ALL patients. Recent genomic studies have provided a refined genetic map of acute lymphoblastic leukemia (ALL) ... Read more