INTRODUCTION: Angiogenesis is an essential requirement for cholesteatoma growth and expansion. It is mediated via variety of cytokines and growth factors like basic fibroblast growth factor (basic-FGF). Localization of basic FGF in cholesteatoma matrix and its correlation with the destructive capacity of cholesteatoma were seldom seen in previous reports. METHODOLOGY: A prospective immunohistochemical study was employed using 19 acquired cholesteatoma ... Read more