Abstract Background:Psoriasis is a chronic inflammatory skin disease that not fully understood till now. Many treatment options has been implicated. Omentin 1 is anew marker implicated in many diseases. Objectives:To show association betweenserum level of Omentin-1 in psoriatic patients and its correlation with psoriasis area and severity index (PASI) score before and after treatment with narrow band ultraviolet B phototherapy ... إقراء المزيد

Psoriasis is one of the most common chronic, inflammatory, T-cell-mediated autoimmune diseases. Narrow-band UVB (NB-UVB) therapy is widely used in the treatment of psoriasis; however, its mechanism of action is still not well understood. The objective of this study was to investigate the circulating T-lymphocyte subpopulations in psoriasis patients before and after NB-UVB, to get insights into the mechanism of ... إقراء المزيد

Psoriasis is one of the most common chronic, inflammatory, T-cell-mediated autoimmune diseases. Narrow-band UVB (NB-UVB) therapy is widely used in the treatment of psoriasis; however, its mechanism of action is still not well understood. The objective of this study was to investigate the circulating T-lymphocyte subpopulations in psoriasis patients before and after NB-UVB, to get insights into the mechanism of ... إقراء المزيد

Objectives: To assess the impact of psoriasis on patients' quality of life. Subjects and Methods: Sixty psoriasis patients were selected among attendants of outpatients clinic, Dermatology and Venereology Depettment, Sohag university and 30 healthy age- and sex-matched subjects served as a control. Results: Quality of life of more than /Jalf of psoriasis patients was bad (51. 7%), compared with 13.3% ... إقراء المزيد

OBJECTIVES: To compare the expression of Bcl-xl (antiapoptotic) and Bax (proapoptotic) factors in psoriatic patients treated with calcipotriol alone with those treated with combination of calcipotriol and mometasone furoate, also to compare the expression of these factors in keratinocytes of lesional with non lesional skin of psoriatic patients and of controls, and lastly to correlate the level of these parameters ... إقراء المزيد