Nerve growth factor (NGF) expression in correlation with severity of pruritus in cirrhotic patients.
BACKGROUND: Hepatic pruritus is a very common symptom among different chronic liver diseases, particularly in those related to cholestasis. Its prevalence is variable among liver diseases, ranging from 5% in chronic hepatitis C virus infection to 70% in primary biliary cirrhosis. Its etiopathogenesis remains poorly understood. Nerve growth factor (NGF) is a member of neurotrophins. many studies clearly demonstrate their ... إقراء المزيد