Tarek T. Ali -

Tarek T. Ali

Professor - Professor

Faculty of science

Address: Chemistry Department, Faculty of Science, Sohag University, Sohag, P.O.Box 82524, Egypt

Publications Which contain the keyword:

Urinary Screening for Detection of Renal Abnormalities in Asymptomatic School Children, Sohag Governorate, Egypt

2020-03-02 21:49:02 Keywords Urinary Screening , , Urinary Screening , , Urinary Screening , , Urinary Screening , UTIs,

Background: Dipstick urine analysis is the most common method for screening children for detecting urinary abnormalities. This study is aimed to estimate the frequency of urinary problems among children aged 6-13 years from five primary schools in different parts of the Sohag Governorate, Egypt. Study Design and Setting: Cross-sectional study carried out by the Pediatrics Department and Community Medicine Departments ... Read more

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

2020-02-04 19:06:32 Keywords HDACs Inhibitors;, Ligustrazine, , Anticancer agents, , In silico study, , Synthesis,

INTRODUCTION: Histone deacetylases (HDACs) represent one of the most validated cancer targets. The inhibition of HDACs has been proven to be a successful strategy for the development of novel anticancer candidates. METHODS: This work describes design and synthesis of a new set of HDAC inhibitors ( 7A-C and 8A, B) utilizing ligustrazine as a novel cap moiety, and achieving the ... Read more

β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice

2019-09-17 11:47:05 Keywords , 4-dihydroxybenzoic acid, 2, 4-dihydroxybenzoic acid, astrogliosis, mitochondrial encephalopathy, Q synthome, spongiosis,

Coenzyme Q (CoQ) deficiency has been associated with primary defects in the CoQ biosynthetic pathway or to secondary events. In some cases, the exogenous CoQ supplementation has limited efficacy. In the Coq9R239X mouse model with fatal mitochondrial encephalopathy due to CoQ deficiency, we have tested the therapeutic potential of b-resorcylic acid (b-RA), a structural analog of the CoQ precursor 4-hydroxybenzoic ... Read more

In-vitro evaluation of Nigella sativa and Punica granatum effect on protoscolices of hydatid cysts

2019-04-30 00:36:40 Keywords Hydatid cyst , Echinococcus gra, granulosus, Nigella sativa, , punica granatum,

Cystic echinococcosis (CE) are commonly found in the liver and lungs of affected hosts. The treatment approach is usually surgical, or giving drugs in conjunction before surgery to kill protoscolices, to avoid anaphylactic shock from leakage of hydatid fluid into the peritoneum and to decrease opportunities for recurrences. The present study was to evaluate the in-vitro scolicidal efficacy of hydroalcoholic ... Read more

Prophylactic and Ameliorative Effect of 𝑁-Acetylcysteine on Doxorubicin-Induced Neurotoxicity in Wister Rats

2019-03-11 09:02:25 Keywords Doxorubicin, N-Acetylcysteine, , neurotoxicity, tumor necrosis,

Doxorubicin (DOX) is an anthracycline antibiotic and a quinone-containing chemotherapeutic drug used for various types of cancers. However, as with most anticancer drugs, it causes many toxic effects, one of them is cognitive impairment. The present study investigated the prophylactic and ameliorative effect of n-acetylcysteine (NAC) against DOXinduced neurotoxicity in rats. Rats were divided into four groups. Control group: rats ... Read more

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

2020-02-04 19:06:32 Keywords HDACs Inhibitors;, Ligustrazine, , Anticancer agents, , In silico study, , Synthesis,

Prevalence of Tissue Parasites in Cattle and Buffaloes Slaughtered in El-Minia Governorate Abattoirs, Egypt

2019-08-24 14:34:00 Keywords Fasciola, , Hydatid, , Cysticercus, Sarcocystis, cattle, Buffalo,

Abstract: The present study was conducted to determine the prevalence of meat borne parasitic infection in 170 animals (120 cattle and 50 buffaloes) slaughtered in El-Minia Governorate abattoirs, during the period from June 2017 to May 2018. The obtained data were statistically analysed by SPSS software using ANOVA test at 95 % confidence level (P ≤ 0.05). The study revealed ... Read more

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

2020-02-04 19:06:32 Keywords HDACs Inhibitors;, Ligustrazine, , Anticancer agents, , In silico study, , Synthesis,

Closed-Chamber Anterior Capsulorhexis Under Air Tamponade In White Cataract

2019-10-19 20:15:49 Keywords air tamponade, white cataract, , intumescent cataract, , phacoemulsification, intumescent cataract, white cataract, capsulorhexis,

Purpose: To evaluate the efficacy and safety of a closed-chamber air bubble capsulotomy technique to prevent the Argentinean flag sign (AFS) in patients with white and intumescent cataracts. Setting: Sohag University, Faculty of Medicine, Ophthalmology Department, Sohag, Egypt. Design: Prospective interventional noncomparative case series. Methods: Eighty-two eyes of 80 patients with white and intumescent cataracts were included. Eyes with any ... Read more

Prevalence of Tissue Parasites in Cattle and Buffaloes Slaughtered in El-Minia Governorate Abattoirs, Egypt

2019-08-24 14:34:00 Keywords Fasciola, , Hydatid, , Cysticercus, Sarcocystis, cattle, Buffalo,

Contact me

AddressChemistry Department, Faculty of Science, Sohag University, Sohag, P.O.Box 82524, Egypt
Emailtarek_ali@science.sohag.edu.eg

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