Role of Nerve Growth Factor (NGF) and Its Receptor Tyrosine Kinase A (TrK A) in Egyptian Cirrhotic Patients with Pruritus.
Background: Pruritus is a distressing symptom of cholestatic, inflammatory,and malignant liver diseases. It is a common symptom in many biliary andcholestatic disorders such as primary biliary cirrhosis (PBC). Several mechanisms are generally accepted as possible explanations to the underlying basis of itch.However, the exact pathophysiology of pruritus in liver diseases remains unclear.The cutaneous and central neurobiology of pruritus is complex ... إقراء المزيد