Von Willibrand Factor Antigen as a Non Invasive Predictor of Portal Hypertension in Patients with Liver Cirrhosis
In cirrhotic livers, increased resistance to portal blood flow is the primary factor in the pathophysiology of portal hypertension (PH) and is caused by structural abnormalities in the hepatic vascular architecture and an increased hepatic vascular tone. Von Willebrand factor antigen (vWF Ag) is released by activated endothelial cells (ECs) and therefore represents an indicator of EC activation and plays ... إقراء المزيد