Luteolin: target validation in Babesia bovis by reverse transcription polymerase chain reaction and in vivo inhibition of Babesia microti
Luteolin, a naturally occurring plant flavonoid, has antioxidant, anti-amoebic, antitrypanosomal, and antimalarial activities. In this study, the inhibitory effects of luteolin were microscopically evaluated against three Babesia species and Theileria equi in vitro and against B. microti in mice. Reverse-transcription PCR was used to evaluate the effect of luteolin on transcription of DNA gyrase subunits A and B genes. Luteolin ... إقراء المزيد