Role of Immunohistochemical Cyclo-oxygenase-2 (COX-2) and Osteocalcin Expression in Differentiating Osteoblastomas from Osteosarcomas
_BACKGROUND/AIMS:_ Differential diagnosis between aggressive osteoblastoma and low grade osteosarcoma may be very difficult or even impossible on a small biopsy. This study was designed to assess the usefulness of immunoexpression of COX-2 and osteocalcin in the differential diagnosis of the two tumour types. _METHODS:_ Immunostaining of COX 2 and osteocalcin were studied in 9 osteoblastomas and 30 osteosarcomas. _RESULTS:_ ... Read more