chronic viral hepatitis and histopathological predictors إقراء المزيد

Occult hepatitis B virus infection (OBI) is characterized by the presence of HBV DNA in the liver tissue or in the serum of HBsAg negative individuals. Although OBI was detected frequently in patients with chronic hepatitis C, the clinical implication of this co-infection is still not fully clarified. The aim of the present study was to assess the prevalence and ... إقراء المزيد

INTRODUCTION: Egypt is estimated to have the highest prevalence of chronic hepatitis C virus infection in the world, with a reported average rate of 14.7%. In addition, chronic hepatitis was found to be an independent risk factor for the development of erectile dysfunction (ED). AIM: To identify the prevalence and risk factors of ED in a sample of HCV-infected patients ... إقراء المزيد

INTRODUCTION: Predictors of SVR to pegylated interferon (PEG-INF) alfa-2a and ribavirin (RBV) therapy in chronic HCV infected patients is very important for therapy. Increased HPCs in HCV-infected patients was correlated with increasing fibrosis and response to treatment. HPCs was detected in the liver by immunohistochemical expressions of cytokeratin (CK) 7 and CK19. AIMS &METHODS: Evaluation of the response rate to ... إقراء المزيد

Abstract Background and Aims: Oesophageal varices (OV) are the most common complication of liver cirrhosis. However, no available data exist on the prevalence and the laboratory predictors of OV in chronic hepatitis C (CHC) Egyptian patients with bridging fibrosis or cirrhosis. Therefore, we aimed to investigate the frequency of OV in these patients and to assess whether simple non-invasive serum ... إقراء المزيد

Chronic HCV with its longstanding complications of cirrhosis and HCC is a highly prevalent and challenging problem in Egypt. Recently, microRNAs are ranked as potential biomarkers for early diagnosis of HCV related complications. The aim of the present study was to evaluate the role of miRNA-122 and miRNA-155 for prediction of progression of HCV infection and for diagnosis of HCC. ... إقراء المزيد

In Egypt, the rate of death/transplantation, decompensation and HCC in patients with compensated HCV cirrhosis is 4.58%, 6.37% and 3.36%, respectively. It is estimated that Egyptian patients with HCV cirrhosis had an annual incidence of HCC with 5.3%. CD34 is a 110-kDa transmembrane glycoprotein present on leukemic cells, endothelial cells and stem cells). CD34 is preferentially expressed on the surface ... إقراء المزيد

Worldwide Egypt had the highest prevalence of hepatitis C virus infection. Angiogenesis is a complex process that regulated by many factors, including vascular endothelial growth factor (VEGF). In the liver hepatic satellite cells (HSCs), Kupffer cells, regenerating hepatocytes and existing endothelial cells are responsible for the process of neoangiogenesis and production of vascular endothelial growth factor (VEGF). AIM OF THE ... إقراء المزيد

AIMS OF THE WORK [1] To assess the pattern of response in chronic HCV infected patients treated with non-interferon antiviral therapy. [2] To study the predictors of non-response to interferon free antiviral therapy in the non-responder and relapsed groups. PATIENTS AND METHODS PATIENTS: Prospective study will be conducted on the patients attending our Tropical Medicine and Gastroenterology outpatient clinic of ... إقراء المزيد

BACKGROUND AND AIMS Oesophageal varices (OV) are the most common complication of liver cirrhosis. However, no available data exist on the prevalence and the laboratory predictors of OV in chronic hepatitis C (CHC) Egyptian patients with bridging fibrosis or cirrhosis. Therefore, we aimed to investigate the frequency of OV in these patients and to assess whether simple non-invasive serum fibrosis ... إقراء المزيد