Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط



Publications Which contain the keyword: β-Catenin

2018-10-23 20:22:05 Keywords Colorectal cancer, adenoma, Carcinoma, , Bcl-2, Bax , P53, Ki-67, , ApopTag, , β-Catenin,
Markers defining colorectal adenoma-carcinoma progression: a computerized image analysis protocol
ABSTRACT: The vast majority of colorectal carcinoma are widely believed to arise from polypoid adenomas. The apoptotic related genes that have been most consistently characterized in colonic cancer are bcl-2, bax, and p53. Studying the expression of these genes in adenoma carcinoma sequence will be of great value in producing the clinical behavior of benign tumors. Loss of contact inhibition ... Read more

2018-10-16 15:17:40 Keywords Bcl-2, Bax, P53, STAT3, β-Catenin, COLON, adenoma, Carcinoma,
Comparative study of Bcl-2, Bax, p53, STAT3 and β-catenin and their relationship to colonic epithelial progression from adenomas to carcinomas: a multiparameter immunohistochemical computerized image analysis study
ABSTRACT: Adenoma-carcinoma sequence was postulated for most colorectal carcinomas. Deregulation of apoptosis & cell proliferation is involved in the pathogenesis of neoplasia. The apoptosis genes characterized in colon cancer are bcl-2, bax & p53. b-catenin plays a role in both cell adhesion & intracellular signaling. Translocation of b-catenin from the cell membrane to the cytoplasm or nucleus is an early ... Read more

2018-09-09 12:37:13 Keywords Mammary Ductal Carcinoma, β-Catenin,
Expression of β-Catenin in Locally Aggressive Mammary Ductal Carcinoma
Background and Aim: β-catenin is a cell membrane mol-ecule that is essential for cell-cell adhesion of normal epithelia. It is down-regulated in several epithelial tumors and its expression is correlated with tumor cell invasion and metasta-sis. The aim of this study was to evaluate expression status and angiogenic effect of β-catenin in locally aggressive mammary carcinoma. Methods: Formalin-fixed paraffin embedded ... Read more

Use of PTEN, PCNA, and β-catenin to differentiate between endometrial hyperplasia and endometrial adenocarcinoma
Background The use of PTEN, PCNA, and β-catenin may be of value to differentiate well differentiated endometrioid carcinoma from complex atypical endometrial hyperplasia. Methods Immunohistochemical evaluation of PTEN, PCNA, and β-catenin was performed on 100 specimens including eight proliferative endometrium, 10 secretory endometrium, 10 simple endometrial hyperplasia, 10 complex typical endometrial hyperplasia, 30 complex atypical endometrial hyperplasia, and 32 endometrioid ... Read more

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