Barrett's esophagus is a well-recognized precursor of esophageal adenocarcinoma. Surveillance of Barrett's esophagus patients is recommended to detect high-grade dysplasia (HGD) or early cancer. Because of wide variation in the published cancer incidence in Barrett's esophagus, the authors undertook a systematic review and meta-analysis of cancer and HGD incidence in Barrett's esophagus. Ovid Medline (Ovid Technologies, Inc., New York, New ... Read more

Introduction Barrett's oesophagus (BO) is a premalignant lesion of the oesophagus that predisposes to oesophageal adenocarcinoma (OAC). Currently, widespread endoscopic surveillance of BO is undertaken in an attempt to detect and treat OAC at an early stage. The cost effectiveness of such surveillance is highly dependant on OAC risk in BO. However, the reported incidence of OAC in BO varies ... Read more

ABSTRACT BACKGROUND: Barrett's esophagus (BE) is a premalignant lesion that predisposes to esophageal adenocarcinoma. However, the reported incidence of esophageal adenocarcinoma in patients with BE varies widely. We examined the risk of malignant progression in patients with BE using data from the Northern Ireland Barrett's esophagus Register (NIBR), one of the largest population-based registries of BE worldwide, which includes every ... Read more