Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae and manifested by an immunological and clinical outcome, ranging from borderline lepromatous and lepromatous infections to tuberculoid and borderline tuberculoid infections. Cytokines such as interleukin (IL)-6, IL-10, interferon-γ (IFN-γ), and tumor necrosis factor-α are associated with leprosy. Objective The aim was to assess IL-6 and IFN-γ in untreated patients ... Read more

Introduction & Objectives Leprosy is a chronic infectious disease caused by Mycobacterium leprae that can manifest a wide variety of immunological and clinical outcomes ranging from lepromatous pole to tuberculoid pole. Different Th 1 and Th2 cytokine profiles are associated with leprosy such as as I L-4,I L-5, I L-6, I L-10, IL-2, IFN-γ and TNF-γ.Aim of the work is ... Read more

Aim was to analyse new cases of leprosy detected annually from 2004-2008 Read more

Leprosy or Hansen’s disease (HD) is a chronic infectious disease caused by Mycobacterium leprae. The ratio of malondialdehyde (MDA)/superoxide dismutase (SOD) may be considered as an index of oxidative stress (OS). Objective To assess the OS by estimating the levels of antioxidant enzyme (SOD), lipid peroxidation products (MDA) and the ratio of MDA/SOD in the skin of paucibacillary (PB) and ... Read more

INTRODUCTION: Leprosy is a chronic and complex infectious illness; the new-case detection rate is better than prevalence as an indicator of disease trends. This study presents an analysis of pattern of new cases of leprosy detected annually from 2004 to 2008 in Sohag Governorate, Upper Egypt. PATIENTS AND METHODS: Data about patients with newly diagnosed leprosy were collected from Sohag ... Read more