lobna.nassr

Lobna Abdel-Mohsen Ebaid Nassr

Professor - Head Of Chemistry Department- Director of Quality Management Unit - Faculty of Science - Sohag University

Faculty of science

Address: Chemistry Department - Faculty of Science - Sohag University

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Publications Which contain the keyword: Antimicrobial activity


Novel Azomethine Pd(II) and VO(II)  Based Metallo-Pharmaceuticals as Anticancer, Antimicrobial and Antioxidant  agents:  Design, Structural inspection,  DFT investigation and DNA interaction
The new NO bi-dentate imine ligand namely (2-[(3-Nitro-benzylidene)-amino]-benzoic acid) (NBA) imine ligand (L) and their Pd(II) and VO(II) complexes have synthesized and characterized utilizing different physiochemical methods including elemental analyses, FT-IR, NMR, molar conductance and magnetic susceptibility measurements. The stability constant of these complexes has also determined. The studies of these complexes were found to have [M (L)] composition where ... Read more

Complexation of Schiff bases incorporating of Salicylaldehyde Derivatives and Amino Acids to Copper(II) as an effective strategy for antimicrobial activity improvement, DNA Interaction and catalytic activity
Five Cu(II) complexes are tridentate Schiff bases amino acids ligands derived from condensation 3–methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with α-amino acids (L-phenylalanine(P), L-histidine (H), DL-tryptophane (T)). All ligands are analyzed by 1HNMR and 13CNMR. The investigated complexes have been prepared and characterized by elemental analysis, infrared spectra, ultraviolet-visible and thermal analysis in dynamic air atmosphere (40ml / min) at a ... Read more

Desighn, Characterization and Biological activity of new mixed ligand transition metal complexes of glutamine, glutaric and glutamic acid with nitrogen based ligands.
A new series of Cu(II), Co(II), Ni(II) and Fe(II) ternary complexes of glutamine, glutaric and glutamic acid with imidazole derivatives have been synthesized. The nature of bonding and the stereochemistry of the complexes have been deduced from elemental analyses, infrared, electronic spectra, conductivity measurements and thermogravimetric analysis. The structure of [Co(glu)(IMI)2] and [Fe(glu)(IMI)2(H2O)2] complexes was validated using quantum mechanics calculations ... Read more

Toxicological and Biological Activities of the Acid Secretion of Berthellina citrina (Heterobranchia, Pleurobranchidae) from the Red Sea
_Berthellina citrina _is a pleurobranchid opisthobranch characterized by its skin acid-secretion that contains sulphate and chloride ions with traces of organic matter. To identify defensive potential and bioactivity, we tested this secretion for the first time against _Artemia salina_, different strains of microorganisms, human RBCs and human cancer cell lines. It showed lethality to _A. salina _with LC50 values 83.86 ... Read more

Synthesis and Antimicrobial Activity of Substituted Nitrotetrazole-5-Carbaldehyde Hydrazones
A series of substituted -nitrotetrazole-5-carbaldehyde hydrazones were synthesized and tested for antimicrobial activity with respect to _Staphylococcus aureus_, _Streptococcus pneumoniae_, _E. coli_, _P. aeruginosa_, and _Micrococcus_. The minimum inhibitory concentrations were determined. Read more

Nano structure Iron (II) and Copper (II) Schiff base complexes of a NNO-tridentate ligand as new antibiotic agents: spectral, thermal behaviors and DNA binding ability
Complexes of Fe (II) and Cu (II) with a tridentate Schiff base, 2-((z)-(pyridine-2-ylimino) methyl) naphthalene1-ol derived from 2-hydroxy-1-napthaldehyde and 2-aminopyridine were synthesized. Both the ligand and its complexes were characterized on the basis of microanalysis, melting point, 1H and 13CNMR, molar conductivity, thermal analysis, IR and UV/Vis spectral studies. From analytical data, the stoichiometry of the complexes was found to ... Read more

2018-09-16 21:50:05 Keywords Antimicrobial activity, Synthesis,
Sonochemical synthesis, DNA binding, antimicrobial evaluation and in vitro anticancer activity of three new nano-sized Cu(II), Co(II) and Ni(II) chelates
Sonochemical synthesis, DNA binding, antimicrobial evaluation and in vitro anticancer activity of three new nano-sized Cu(II), Co(II) and Ni(II) chelates based on tri-dentate NOO imine ligands as precursors for metal oxides Read more

Three novel Ni(II), VO(II) and Cr(III) mononuclear complexes: Synthesis, structural characterization, DNA interaction, antimicrobial evaluation and anticancer activity
Three novel Cr(III),VO(II) and Ni(II) imine complexes derived from the condensation of 2‐aminophenol (AP) with 2‐hydroxynaphthaldehyde (HN) were synthesized. The prepared HNAP imine ligand and its complexes were investigated via various physicochemical tools. The results suggest that the parent ligand behaves as a dibasic tridentate ONO ligand, when coordinated to Cr(III) in octahedral and to Ni(II) in tetrahedral geometry. In ... Read more

Design and nonlinear optical properties (NLO) using DFT approach of new chelates for DNA interaction, antimicrobial, anticancer activities and molecular docking studies
In recent years, metals based antitumor complexes have played a vital role in chemotherapy. Therefore, in this study, some new imine Cr(III), VO(II) and Ni(II) complexes incorporating ESAP imine ligand (2-Ethoxy-6-((2-hydroxy-phenylimino)-methyl)-phenol were designed and synthesized. The investigated complexes were fully characterized by micro analysis, infrared, electronic spectra, thermal analysis(TGA), conductivity as well as magnetic susceptibility measurements. Moreover, the stability constants ... Read more

DNA interaction, antimicrobial, anticancer activities and molecular docking study of some new VO(II), Cr(III), Mn(II) and Ni(II) mononuclear chelates encompassing quaridentate imine ligand
The present study was conducted to synthesis of some new imine Cr(III), VO(II), Mn(II) and Ni(II) complexes derived from the condensation of 2-amino phenol with 2-hydroxynapthaldehyde were synthesized. The prepared HNPN imine ligand was analyzed by its melting point, IR, 1H NMR and 13C NMR spectroscopies. The investigated HNPN imine complexes were characterized by elemental analysis, FT IR, UV–vis and ... Read more