ahmedabudief

Prof. Ahmed Mohamed Abu-Dief

Professor - Professor of Physical and Inorganic Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

348

Like
22 103 272 150 5 107 7.8K 31K
275

Newly Added
  • Courses 22
  • Course Supplements 103
  • Courses Tasks 272
  • Publications 150
  • Office hours 5
  • Announcements 107
  • File uploaded 135
  • Downloaded Times 1396

Publications Which contain the keyword: Molecular modeling

Metal based pharmacologically active agents: Synthesis, structural characterization, molecular modeling, CT-DNA binding studies and in vitro antimicrobial screening of iron(II) chelates

2018-09-16 14:17:18 Keywords amino acid, TGA, Antimicrobial, Gel electrophoresis, Calf thymus DNA, Molecular modeling, Fe(II) chelates, Schiff bases,
Metal based pharmacologically active agents: Synthesis, structural characterization, molecular modeling, CT-DNA binding studies and in vitro antimicrobial screening of iron(II) chelates
In recent years, great interest has been focused on Fe(II) Schiff base amino acid complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 5-bromosalicylaldehyde (bs) and α-amino acids (l-alanine (ala), l-phenylalanine (phala), l-aspartic acid (aspa), l-histidine (his) and l-arginine (arg)). The ... Read more

Synthesis, structure elucidation, biological screening, molecular modeling and DNA binding of some Cu(II) chelates incorporating imines derived from amino acids

2018-09-11 15:03:04 Keywords Amino acids, Imine, Molecular modeling, Antimicrobial, Antiviral, DNA, IR, TGA, complexes,
Synthesis, structure elucidation, biological screening, molecular modeling and DNA binding of some Cu(II) chelates incorporating imines derived from amino acids
Three tridentate Schiff bases amino acids were prepared by direct condensation of 3-methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with α-amino acid ligands [l-phenylalanine (P), l-histidine (H) and DL-tryptophan (T)]. The prepared Schiff bases amino acids were investigated by melting points, elemental analysis, 1HNMR and 13CNMR, IR, UV–Vis spectra, conductivity and magnetic measurements analyses. Subsequently, copper was introduced and Cu(II) complexes formed. ... Read more

  • «
  • 1
  • »