ahmedabudief

Prof. Ahmed Mohamed Abu-Dief

Professor - Professor of Physical and Inorganic Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: Intercalation


2020-03-19 10:52:40 Keywords DNA, Anticancer, Drug, Intercalation, Minor Grooving, Cisplatin,
DNA Interaction of Drug Molecules for Cancer Treatment
The deoxyribonucleic acid (DNA) is the molecule of life that controls all the chemical changes that take place in cells. It is the molecular target for many of the drugs that are used in cancer therapeutics, and is viewed as a non-specific target of cytotoxic agents. The interaction of drugs with DNA is among the most important aspects of biological ... Read more

Tailoring, physicochemical characterization, antibacterial and DNA binding mode studies of Cu(II) Schiff bases amino acid bioactive agents incorporating 5-bromo-2-hydroxybenzaldehyde
Five novel Cu(II) complexes derived from the condensation between 5-bromosalicylaldehyde (bs) and α-amino acids (L-alanine, l-phenylalanine, L-aspartic acid, L-histidine and L-arginine) were synthesized and characterized by their elemental analyses, thermogravimetric analysis, IR, mass and electronic spectra, conductance and magnetic measurements. Moreover, the stoichiometry and the stability constants of the prepared complexes have been determined spectrophotometrically using continuous variation and molar ... Read more

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