Curcumin has been proved to have antioxidant and antiinflammatory actions. We investigated the prophylactic effect of curcumin against the development of non-alcoholic fatty liver (NAFLD) disease in high fat diet (HFD)-fed rats. The study included three groups of rats, group I were fed low-fat diet, group II were fed HFD and group III were fed HFD and curcumin at a ... Read more

Starting with curcumin different pyrane, N-phenyl-1,3-thiazolidin and thiocurcumin derivatives were synthesized. 4-Oxo-3-phenyl1,3-thiazolidin derivative was reacted with different organic reagents examply, benzaldehyde, triethylorthoformate and hydrazine hydrate to form new series of 5-benzylidine-4-oxo-3-phenyl-1,3-thiazolidin, 5-ethoxymethylene-4-oxo-3-phenyl-1,3-thiazolidin and [1,8] naphthyridine derivatives. Some of these derivatives were evaluated as anti- inflammatory agents. All compounds have been characterized by spectral analyses. Read more

INTRODUCTION: Smoking can affect hormone secretion; some of these effects are associated with important clinical implications. These effects are mainly mediated by the action of nicotine. Curcumin is a well known antioxidant agent. AIM OF THE WORK: To study the protective role of curcumin against nicotine induced toxic effects on the adrenal medulla. METHODS: Thirty adult male mice were used ... Read more

Nicotine is a major toxic component of cigarette smoke. Cigarette smoking alters the levels of endogenous steroid hormones. Curcumin is a well known antioxidant agent. Aim of the Work: To study the protective role of curcumin against nicotine induced toxic effects on the adrenal cortex. Materials and Methods: Thirty adult male mice were used and were divided into three groups ... Read more

Starting with curcumin different pyrane, N-phenyl-1,3-thiazolidin and thiocurcumin derivatives were synthesized. 4-Oxo-3-phenyl1,3-thiazolidin derivative was reacted with different organic reagents examply, benzaldehyde, triethylorthoformate and hydrazine hydrate to form new series of 5-benzylidine-4-oxo-3-phenyl-1,3-thiazolidin, 5-ethoxymethylene-4-oxo-3-phenyl-1,3-thiazolidin and [1,8] naphthyridine derivatives. Some of these derivatives were evaluated as anti- inflammatory agents. All compounds have been characterized by spectral analyses. Read more

protective effect of curcumin on the liver of high fat diet fed rats Read more