Stemness-related transcriptional factors and homing gene expression profiles in hepatic differentiation and cancer
Stem cell transcriptional signature activation is an essential event in the development of cancer. This study aimed to investigate the differential expression profile of three pluripotency-associated genes (_OCT4_, _NANOG_, and _SOX2_), G-protein-coupled chemokine receptor 4 (_CXCR4_) and the ligand (_CXCL2_), and alpha feto-protein (_AFP_) in hepatogenic differentiated stem cells and in sera of hepatitis C virus (HCV) and HCV-induced hepatocellular ... Read more