Evaluation of the Proliferation Index and p53 Protein Expression in Preinvasive and Invasive Breast Carcinoma
BACKGROUND: Breast cancer is the most frequently diagnosed cancer and the most common cause of cancer deaths in women worldwide. Ki67 is a biomarker that reflects cell proliferation. Despite a clear understanding of the structure and properties of this protein, its functional role remains elusive. Gene expression alteration confers the potential for invasive growth in the preinvasive stages of breast ... Read more