ABSTRACT _AIM:_ to evaluate safety and efficacy of harmonic scalpel in closure/division of the cystic duct and artery, and bladder dissection in laparoscopic cholecystectomy as a single working instrument, with the use of two working trocars technique, compared with regular laparoscopic clip/cautery, three trocars technique. _METHOD: _A prospective study included 160 patients with symptomatic gall stone disease were randomly assigned ...
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