Objective: To determine insulin resistance in chronic hepatitis C patients and assess the effects of insulin resistance on laboratory and histopathological parameters of chronic hepatitis C. Methodology: The study included 50 person divided into 30 adult chronic hepatitis C patients diagnosed by PCR within previous 6 months and 20 healthy controls. The functional and morphological status of the liver was ... إقراء المزيد

Background: Liver cirrhosis is a catabolic disease characterized by decreased adipose tissue mass and a proinflammatory state. Although hyperinsulinemia and insulin resistance are commonly found in these patients, their exact mechanisms are not fully understood. Among the candidate mediators, the adipokines resistin and adiponectin have been incriminated in experimental animal models. Their exact role in cirrhotic patients remains a subject ... إقراء المزيد

_BACKGROUND:_ Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in reproductive age women, yet its clinical presentation shares similarities with several other endocrine disorders such as thyroid disease. Hence, the objective of this study was to further evaluate this association by investigating the clinical, hormonal, and metabolic parameters between subclinical hypothyroidism (SCH) and PCOS. _METHODS:_ This is a cross-sectional ... إقراء المزيد