Abstract: Endometriosis is a common, complex and chronic disease related to ectopic implantation and growth of endometrial tissue. Endometriosis is characterized by the presence and/or the growth of endometrial tissue (both glands and stroma) outside the uterine cavity that causes inflammation inside or outside the pelvis. This study aimed to investigate the possible role of COX-2 in endometriosis and its ... Read more

The study was carried out on 40 patients with Alopecia Areata (AA) attending Dermatology Outpatient Clinic of Sohag University Hospital. 85% had localized AA and 15% had alopecia totalis. 10 healthy individuals were selected as a control.The age of patients ranged from 6 to 50 years with a mean 23.93±12.42 years. Males were 62.5% and females were 37 .5 % ... Read more

CONVENTIONAL THERAPY FOR EARLY INFLAMMATORY ARTHRITIS DOES NOT MODIFY PERIPHERAL BLOOD CYTOKINE PROFILES Nicola J Gullick, David M Jayaraj, Hanan S Abozaid, Hayley G Evans, David L Scott, Ernest Choy, Leonie S Taams BACKGROUND: Many patients with early inflammatory arthritis (EIA) have inadequate responses to initial therapy, even if combination DMARDs and steroids are used at an early stage. We ... Read more

BACKGROUND AND AIMS: There is a debate whether the majority of gastritis mucosal injury occurs as a direct effect of _H. pylori_ infection or as a result of immune cell damage from abundant mediators of inflammatory response. Recently, Urocortin (UCN) has emerged as a mediator of gastrointestinal (GI) responses to noxious stimuli. Interleukins-1β (IL-1β) and interleukin-10 (IL-10) may play important ... Read more