Reaction of dif luorocarbene with 2Hazirines: generation and transformations of strained azomethine ylides — aziriniodifluoromethanides
The reaction of difluorocarbene with azirines affords a new type of azomethine ylides, viz., strained aziriniodifluoromethanides. 1,3Dipolar cycloadditions of ylides derived from 2unsubstituted 3arylazirines to dimethyl acetylenedicarboxylate and aldehydes give deriva tives of 2,2difluoro1azabicyclo[3.1.0]hex3ene3,4dicarboxylic acids and 1,4oxazin 3(4H )ones, respectively. Ylides derived from 2mono and 2,2disubstituted azirines undergo isomerization to 2aza1,3diene derivatives. 2,2Difluoro1azabicyclo[3.1.0]hex3enes are transformed into 2fluoropyridine derivatives in high ... إقراء المزيد