Expression of Cyclooxygenase-2 (COX-2) and Interleukin-8 (IL-8) in H. pylori Gastritis; A Study on Diagnostic Methods and Pathological Effects of H. pylori Infection in Dyspeptic Patients
_BACKGROUND__ H. pylori_ infection causes diverse clinical outcomes, including dyspepsia, peptic ulceration, gastric carcinoma and mucosa associated lymphoid tissue (MALT) lymphoma. Up-regulation of COX-2 has been observed in _H. pylori_ gastritis in response to inflammatory cytokines. IL-8 is a major activator for neutrophils which contribute to mucosal damage in _H. pylori_ infected patients. A wide-spread use of non-invasive simple diagnostic ... Read more