Urocortin and cytokines in gastric mucosa: Relationship to inflammatory activity before and after medical eradication of Helicobacter pylori.
BACKGROUND AND AIMS: There is a debate whether the majority of gastritis mucosal injury occurs as a direct result of _H. pylori_ infection or as a result of immune cell damage from abundant mediators of inflammatory response. Recently, Urocortin (Ucn) has emerged as a mediator of the gastrointestinal (GI) responses to noxious stimuli. Interleukins 1β (IL-1β) and interleukin-10 (IL-10) may ... Read more