amira_fouad

اميره مراد فؤاد حمدي حسين

مدرس - مدرس. كيمياء. حيويه. طبيه

كلية الطب

العنوان: ش. جمال عبد الناصر (العشرين). الشرق. سوهاج. مصر

2

إعجاب

المنشورات و المؤلفات التي تحتوي علي الكلمة المفتاحية: 3-bromopyruvate


2020-04-01 19:58:50 الكلمات المفتاحية Gliomas, 3-bromopyruvate,
Glioma Spheroid Cells (3D Tumor Models) Are Less Responsive to 3-Bromopyruvate than Cultured Cells: Lack of Tumors Eradication.
BACKGROUND : Gliomas and glioblastomas are space-occupying brain tumors with variable aggressive behaviour. Glioblastomas are the most lethal brain tumors and are not responsive to current chemotherapy and radiotherapy. To date, no satisfactory curative treatment exists. 3-bromopyruvate (3BP) is a promising chemotherapeutic that proved effective in treating gliomas and other malignancies in so many reported studies. 3BP is both an ... إقراء المزيد

2018-10-05 16:22:31 الكلمات المفتاحية melanoma, Warburg effect, lact, melanoma, Warburg effect, lactate dehydrogenase, 3-bromopyruvate, paracetamol,
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
3-Bromopyruvate (3BP) is a new, promising anticancer alkylating agent with several notable functions. In addition to inhibiting key glycolysis enzymes including hexokinase II and lactate dehydrogenase (LDH), 3BP also selectively inhibits mitochondrial oxidative phosphorylation, angiogenesis, and energy production in cancer cells. Moreover, 3BP induces hydrogen peroxide generation in cancer cells (oxidative stress effect) and competes with the LDH substrates pyruvate ... إقراء المزيد

2018-10-10 03:50:59 الكلمات المفتاحية 3-bromopyruvate, melanoma, 3-bromopyruvate, melanoma, Warburg effect, lactate dehydrogenase, paracetamol,
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
3-Bromopyruvate (3BP) is a new, promising anticancer alkylating agent with several notable functions. In addition to inhibiting key glycolysis enzymes including hexokinase II and lactate dehydrogenase (LDH), 3BP also selectively inhibits mitochondrial oxidative phosphorylation, angiogenesis, and energy production in cancer cells. Moreover, 3BP induces hydrogen peroxide generation in cancer cells (oxidative stress effect) and competes with the LDH substrates pyruvate ... إقراء المزيد

2018-10-10 03:50:59 الكلمات المفتاحية 3-bromopyruvate, melanoma, 3-bromopyruvate, melanoma, Warburg effect, lactate dehydrogenase, paracetamol,
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
3-Bromopyruvate (3BP) is a new, promising anticancer alkylating agent with several notable functions. In addition to inhibiting key glycolysis enzymes including hexokinase II and lactate dehydrogenase (LDH), 3BP also selectively inhibits mitochondrial oxidative phosphorylation, angiogenesis, and energy production in cancer cells. Moreover, 3BP induces hydrogen peroxide generation in cancer cells (oxidative stress effect) and competes with the LDH substrates pyruvate ... إقراء المزيد

2018-09-19 12:30:00 الكلمات المفتاحية 3-bromopyruvate,
Warburg effect increase steady - state Ros condition in cancer cells throughout decreasing their antioxidant capacities (anti cancer effect of 3-bromopyruvate)
Cancer cells have high metabolic rate in active state using lactic acid instead of pyruvate used by normal cells إقراء المزيد

2018-09-20 08:47:25 الكلمات المفتاحية melanoma, 3-bromopyruvate,
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: A concise literature review and case study
3-Bromopyruvate (3BP) is a new, promising anticancer alkylating agent with several notable functions. In addition to inhibiting key glycolysis enzymes including hexokinase II and lactate dehydrogenase (LDH), 3BP also selectively inhibits mitochondrial oxidative phosphorylation, angiogenesis, and energy production in cancer cells. Moreover, 3BP induces hydrogen peroxide generation in cancer cells (oxidative stress effect) and competes with the LDH substrates pyruvate ... إقراء المزيد

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