Reaction of 2-guanidinobenzoxazole with several halogenated active methylene compounds has revealed formation of the corresponding dihydroimidazole derivatives under solvent free conditions in excellent yield. The anti-bacterial evaluation of the newly synthesized products against different types of Gram-positive and Gramnegative bacteria was performed. Most of products showed high inhibitory effect. The structure of all compounds has been characterized by on IR, ... إقراء المزيد