Objective: Amyloid deposition in multiple myeloma (MM) may lead to an arthropathy resembling rheumatoid arthritis (RA). Since a systematic description of its natural history is lacking, we have performed a systematic analysis of all published cases. Methods: Literature review featuring backward and forward database searches and direct inspection of reference lists. Inclusion criteria were as follows: publication between 1931 and ... Read more

Solitary plasmacytomas of bone involve vertebral bodies in one-third of patients and frequently affect men (70%). The median age of those affected is 56 years. A monoclonal protein in the serum is observed in 24% to 54% of patients, but in the remaining cases no detectable monoclonal protein is seen. Read more